2-(2,5-Dichlorophenyl)-1-(morpholin-4-yl)ethanethione

Base Information

• Chemical Name: 2-(2,5-Dichlorophenyl)-1-(morpholin-4-yl)ethanethione
• CAS No.: 67643-08-7
• Molecular Formula: C₁₂H₁₃Cl₂NOS
• Molecular Weight: 290.213
• NSC Number: 24139
• DSSTox Substance ID: DTXSID20282083
• Wikidata: Q82016264
• Mol file: 67643-08-7.mol

Synonyms:67643-08-7;2-(2,5-dichlorophenyl)-1-(morpholin-4-yl)ethanethione;NSC24139;DTXSID20282083;NSC-24139;AKOS005216913

Chemical Property of 2-(2,5-Dichlorophenyl)-1-(morpholin-4-yl)ethanethione

Chemical Property:

• Vapor Pressure: 1.07E-06mmHg at 25°C
• Boiling Point: 402.8°Cat760mmHg
• Flash Point: 197.4°C
• Density: 1.367g/cm³
• XLogP3: 2.8
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 2
• Exact Mass: 289.0094906
• Heavy Atom Count: 17
• Complexity: 271

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1COCCN1C(=S)CC2=C(C=CC(=C2)Cl)Cl

Technology Process of 2-(2,5-Dichlorophenyl)-1-(morpholin-4-yl)ethanethione

There total 3 articles about 2-(2,5-Dichlorophenyl)-1-(morpholin-4-yl)ethanethione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

morpholine (110-91-8,99108-56-2) + 2,5-dichlorostyrene (1123-84-8) → 4-[(2,5-dichloro-phenyl)-thioacetyl]-morpholine (67643-08-7)

Guidance literature:

With sulfur;

DOI:10.1021/ja01215a058

Reference yield:

morpholine (110-91-8,99108-56-2) + 2,5-dichloroacetophenone (2476-37-1) → 4-[(2,5-dichloro-phenyl)-thioacetyl]-morpholine (67643-08-7)

Guidance literature:

With sulfur;

DOI:10.1021/jo01127a004

Reference yield:

→ 4-[(2,5-dichloro-phenyl)-thioacetyl]-morpholine (67643-08-7)

Guidance literature:

Acetophenon IX ,Schwefel,Morpholin;

upstream raw materials:

morpholine

2,5-dichloroacetophenone

2,5-dichlorostyrene

Downstream raw materials:

2-(2,5-dichlorophenyl)acetic acid