1,1,2,2-Tetramethyl-3-methylenecyclopropane

Base Information

• Chemical Name: 1,1,2,2-Tetramethyl-3-methylenecyclopropane
• CAS No.: 54376-39-5
• Molecular Formula: C8H14
• Molecular Weight: 110.199
• Hs Code.: 2902199090
• DSSTox Substance ID: DTXSID10969477
• Nikkaji Number: J142.858F
• Wikidata: Q82952494
• Mol file: 54376-39-5.mol

Synonyms:Cyclopropane, tetramethylmethylene-;54376-39-5;1,1,2,2-Tetramethyl-3-methylenecyclopropane;DTXSID10969477;GUKKNVZJTXTEBF-UHFFFAOYSA-N;Tetramethyl(methylidene)cyclopropane;2,2,3,3-tetramethylmethylenecyclopropane;1,1,2,2-Tetramethyl-3-methylenecyclopropane #

Chemical Property of 1,1,2,2-Tetramethyl-3-methylenecyclopropane

Chemical Property:

• Vapor Pressure: 69.4mmHg at 25°C
• Boiling Point: 88.2°Cat760mmHg
• Flash Point: °C
• PSA: 0.00000
• Density: 0.79g/cm³
• LogP: 2.60860
• XLogP3: 2.7
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 0
• Rotatable Bond Count: 0
• Exact Mass: 110.109550447
• Heavy Atom Count: 8
• Complexity: 122

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1(C(=C)C1(C)C)C

Technology Process of 1,1,2,2-Tetramethyl-3-methylenecyclopropane

There total 1 articles about 1,1,2,2-Tetramethyl-3-methylenecyclopropane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

3,5-dihydro-3,3,5,5-tetramethyl-4-methylene-4H-pyrazole (55790-78-8) → 2,2-dimethyl-1-(2-methylethylidene)cyclopropane (1121-36-4) + 1,1,2,2-Tetramethyl-3-methylenecyclopropane (54376-39-5) + 5,5-dimethyl-4-propan-2-ylidene-1H-pyrazole (106251-09-6)

Guidance literature:

In pentane; at 20 ℃; Yields of byproduct given; Irradiation;

DOI:10.1021/ja00238a040

Reference yield: 83.0%

1,1,2,2-Tetramethyl-3-methylenecyclopropane (54376-39-5) + benzaldehyde (100-52-7) → 2,2,3,3-tetramethyl-1-phenylpent-4-en-1-one (1182218-30-9)

Guidance literature:

With bis(1,5-cyclooctadiene)nickel ⁽⁰⁾; tributylphosphine; In toluene; at 60 ℃; for 4h; Inert atmosphere;

DOI:10.1021/ja9046894

Reference yield: 81.0%

1,1,2,2-Tetramethyl-3-methylenecyclopropane (54376-39-5) + mesitylenecarbonitrile oxide (2904-57-6) → 1,1,2,2-Tetramethyl-6-(2,4,6-trimethylphenyl)-4-oxa-5-azaspiro<2.4>hept-5-ene (132540-51-3)

Guidance literature:

In diethyl ether; at 80 ℃; for 24h;

upstream raw materials:

3,5-dihydro-3,3,5,5-tetramethyl-4-methylene-4H-pyrazole

Downstream raw materials:

2,3,3-Trimethyl-1,4-pentadiene

5,5,6-Trimethyl-4-methylen-2,6-heptadiensaeure-methylester

1,1,2,2-Tetramethylspiro<2,3>hexan-5-carbonsaeure-methylester

1,1,2,2-Tetramethyl-6-(2,4,6-trimethylphenyl)-4-oxa-5-azaspiro<2.4>hept-5-ene