3-Carbamoyl-1-methylpyridinium iodide

Base Information

• Chemical Name: 3-Carbamoyl-1-methylpyridinium iodide
• CAS No.: 6456-44-6
• Molecular Formula: C7H9 N2 O . I
• Molecular Weight: 264.066
• Hs Code.: 2933399090
• European Community (EC) Number: 229-263-1
• NSC Number: 23359
• Mol file: 6456-44-6.mol

Synonyms:6456-44-6;3-Carbamoyl-1-methylpyridinium iodide;3-carbamoyl-1-methylpyridin-1-ium iodide;1-Methylnicotinamide iodide;Nicotinamide methiodide;1-METHYL-NICOTINAMIDE IODIDE;3-(Aminocarbonyl)-1-methylpyridinium iodide;1-methylpyridin-1-ium-3-carboxamide;iodide;EINECS 229-263-1;NSC 23359;Pyridinium, 3-carbamoyl-1-methyl-, iodide;Pyridinium, 3-(aminocarbonyl)-1-methyl-, iodide;SCHEMBL4082736;N-METHYLNICOTINAMIDE IODIDE;NSC23359;MFCD00031898;NSC-23359;AKOS003234775;CS-O-05891;CS-W010134;3-carbamoyl-1-methylpyridin-1-iumiodide;LS-132157;FT-0636155;D80780

Chemical Property of 3-Carbamoyl-1-methylpyridinium iodide

Chemical Property:

• Vapor Pressure: 9.07E-21mmHg at 25°C
• Melting Point: 189-191°C
• Boiling Point: 723.2°C at 760 mmHg
• Flash Point: 391.2°C
• PSA: 46.97000
• Density: 1.24g/cm³
• LogP: -2.68570
• Storage Temp.: Refrigerator
• Solubility.: DMSO (Slightly), Methanol (Slightly, Sonicated), Water (Slightly)
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 1
• Exact Mass: 263.97596
• Heavy Atom Count: 11
• Complexity: 136

Purity/Quality:

99% ^*data from raw suppliers

1-Methyl-nicotinamide iodide ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: C[N+]1=CC=CC(=C1)C(=O)N.[I-]
• Uses: A nicotinic acid derivative which shows a dopaminergic neurotoxicity A nicotinic acid derivative which shows a dopaminergic neurotoxicity.

Technology Process of 3-Carbamoyl-1-methylpyridinium iodide

There total 10 articles about 3-Carbamoyl-1-methylpyridinium iodide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

nicotinamide (98-92-0,1255150-40-3) + methyl iodide (74-88-4) → N-methylnicotineamide iodide (6456-44-6)

Guidance literature:

In ethanol; for 0.333333h; Solvent; Wavelength; Temperature; Microwave irradiation;

DOI:10.3390/molecules24061001

Reference yield:

orotate anion (73-97-2) + C7H9N2O (42986-37-8) → N-methylnicotineamide iodide (6456-44-6) + 2,6-Dioxo-1,2,3,6-tetrahydro-pyrimidine-4-carboxylic acid anion (73-97-2)

Guidance literature:

In water; at 20 ℃; Rate constant; Equilibrium constant; pH 8.6;

Reference yield:

C7H9N2O (42986-37-8) + uridine (58-96-8) → N-methylnicotineamide iodide (6456-44-6) + C9H12N2O6(1-)

Guidance literature:

In water; at 20 ℃; Rate constant; Equilibrium constant; pH 8.2-8.7;

upstream raw materials:

nicotinamide

methyl iodide

piperidine

3-cyano-1-methylpyridinium iodide

Downstream raw materials:

4-cyano-1,4-dihydro-N-methylpyridine-3-carboxamide

1-methylnipecotamide

1-methyl-1,4-dihydronicotinamide

1-methyl-2-pyridone-5-carboxamide

Refernces

• 1、 -. "COMPOUNDS FOR PROMOTING FOLLICLE MATURATION". Page/Page column 18. . Retrieved 2021/07/17.
• 2、 Tan, Hailiang,Wang, Jie,Zhang,Xing, Yongning,Sun, Qi,Li, Runtao. "Tandem synthesis of substituted 2,7-naphthyridin-1(7H)-ones via Reissert reaction/intramolecular nucleophilic addition/oxidation dehydrogenation". . p. 8299 - 8304. Retrieved 2013/09/02.