6-Amino-1-ethyl-3-propyluracil

Base Information

Chemical Name:6-Amino-1-ethyl-3-propyluracil
CAS No.:63981-31-7
Molecular Formula:C₉H₁₅N₃O₂
Molecular Weight:197.237
Hs Code.:
NSC Number:28902
DSSTox Substance ID:DTXSID20981605
Nikkaji Number:J96.606A
Wikidata:Q82968014

Synonyms:63981-31-7;6-Amino-1-ethyl-3-propyluracil;6-amino-1-ethyl-3-propylpyrimidine-2,4(1h,3h)-dione;6-amino-1-ethyl-3-propylpyrimidine-2,4-dione;6-Amino-1-ethyl-3-propyl-1,2,3,4-tetrahydropyrimidine-2,4-dione;72361-28-5;Uracil, 6-amino-1-ethyl-3-propyl-;SC-2614;BRN 0162762;6-Amino-1-ethyl-3-propyl-2,4(1H,3H)-pyrimidinedione;NSC28902;2,4(1H,3H)-Pyrimidinedione, 6-amino-1-ethyl-3-propyl-;SCHEMBL239409;1-ethyl-3-propyl-6-aminouracil;DTXSID20981605;MFCD01677158;NSC 28902;NSC-28902;SB56618;AS-83112;LS-158547;LS-158549;CS-0050351;FT-0698742;P17988;2,3H)-Pyrimidinedione, 6-amino-1-ethyl-3-propyl-;6-amino-1-ethyl-3-propyl-1,3-dihydropyrimidine-2,4-dione;2,4(1H,3H)-Pyrimidinedione, 6-amino-1(or 3)-ethyl-3(or 1)-propyl-

Suppliers and Price of 6-Amino-1-ethyl-3-propyluracil

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
6-Amino-1-ethyl-3-propyl-2,4(1H,3H)-pyrimidinedione
2.5g
$ 1320.00

Crysdot
6-Amino-1-ethyl-3-propylpyrimidine-2,4(1H,3H)-dione 95+%
1g
$ 772.00

Chemenu
6-Amino-1-ethyl-3-propylpyrimidine-2,4(1H,3H)-dione 95%
1g
$ 729.00

American Custom Chemicals Corporation
6-AMINO-1-ETHYL-3-PROPYLURACIL 95.00%
1G
$ 1575.00

American Custom Chemicals Corporation
6-AMINO-1-ETHYL-3-PROPYLURACIL 95.00%
5MG
$ 499.97

Total 11 raw suppliers

Chemical Property of 6-Amino-1-ethyl-3-propyluracil

Chemical Property:

Vapor Pressure:0.00184mmHg at 25°C
Boiling Point:292.4°Cat760mmHg
Flash Point:130.6°C
PSA：70.02000
Density:1.146g/cm³
LogP:0.60330
XLogP3:0.2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:197.116426730
Heavy Atom Count:14
Complexity:286

Purity/Quality:

99%, ^*data from raw suppliers

6-Amino-1-ethyl-3-propyl-2,4(1H,3H)-pyrimidinedione ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCCN1C(=O)C=C(N(C1=O)CC)N
Uses 6-Amino-1-ethyl-3-propyluracil is an intermediate in the synthesis of a series of new substituted Xanthines which have high affinity and selectivity for the human adenosine A2B receptors, and thus can be used as clinical candidate for chronic inflammatory airway diseases.

Technology Process of 6-Amino-1-ethyl-3-propyluracil

There total 6 articles about 6-Amino-1-ethyl-3-propyluracil which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 879328-64-0
6-[1-aza-2-(dimethylamino)vinyl]-1-ethyl-3-propyl-1,3-dihydropyrimidine-2,4-dione

: 63981-31-7
6-amino-1-ethyl-3-propylpyrimidine-2,4(1H,3H)-dione

Guidance literature:: In methanol; ammonium hydroxide;

Reference yield:

: 1055299-66-5
6-[1-aza-2-(dimethylamino)vinyl]-1-ethyl-3-propyl-1,3-dihydropyrimidine-2,4-dione

: 63981-31-7
6-amino-1-ethyl-3-propylpyrimidine-2,4(1H,3H)-dione

Guidance literature:: With ammonia; In methanol; water; at 20 ℃; for 72h;

Reference yield:

: 41862-09-3
1-ethyl-6-aminouracil

: 63981-31-7
6-amino-1-ethyl-3-propylpyrimidine-2,4(1H,3H)-dione

Guidance literature:: Multi-step reaction with 3 steps

1: N,N-dimethyl acetamide

2: potassium carbonate / N-methyl-acetamide

3: dichloromethane; aqueous ammonia; methanol

With potassium carbonate; In N-methyl-acetamide; methanol; aqueous ammonia; dichloromethane; N,N-dimethyl acetamide;