L-Leucine, N-[O-(1,1-dimethylethyl)-N-[O-(1,1-dimethylethyl)-N-[N-[N-[(phenylmeth oxy)carbonyl]-L-alanyl]-L-a-aspartyl]-L-seryl]-L-threonyl]-, bis(1,1-dimethylethyl) ester

Base Information

Chemical Name:L-Leucine, N-[O-(1,1-dimethylethyl)-N-[O-(1,1-dimethylethyl)-N-[N-[N-[(phenylmeth oxy)carbonyl]-L-alanyl]-L-a-aspartyl]-L-seryl]-L-threonyl]-, bis(1,1-dimethylethyl) ester
CAS No.:95525-64-7
Molecular Formula:C₄₄H₇₃N₅O₁₂
Molecular Weight:864.09
Hs Code.:

L-Leucine,
N-[O-(1,1-dimethylethyl)-N-[O-(1,1-dimethylethyl)-N-[N-[N-[(phenylmeth
oxy)carbonyl]-L-alanyl]-L-a-aspartyl]-L-seryl]-L-threonyl]-,
bis(1,1-dimethylethyl) ester

Synonyms:

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Chemical Property of L-Leucine, N-[O-(1,1-dimethylethyl)-N-[O-(1,1-dimethylethyl)-N-[N-[N-[(phenylmeth oxy)carbonyl]-L-alanyl]-L-a-aspartyl]-L-seryl]-L-threonyl]-, bis(1,1-dimethylethyl) ester

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Technology Process of L-Leucine, N-[O-(1,1-dimethylethyl)-N-[O-(1,1-dimethylethyl)-N-[N-[N-[(phenylmeth oxy)carbonyl]-L-alanyl]-L-a-aspartyl]-L-seryl]-L-threonyl]-, bis(1,1-dimethylethyl) ester

There total 2 articles about L-Leucine, N-[O-(1,1-dimethylethyl)-N-[O-(1,1-dimethylethyl)-N-[N-[N-[(phenylmeth oxy)carbonyl]-L-alanyl]-L-a-aspartyl]-L-seryl]-L-threonyl]-, bis(1,1-dimethylethyl) ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1142-20-7
N-Cbz-Ala

: 95525-64-7
Z_.Ala_.Asp(OtBu).Ser(tBu).Thr(tBu).Leu(OtBu)

Guidance literature:: Multi-step reaction with 2 steps

1: N-methylmorpholine / dimethylformamide / 0.33 h / 15 °C

2: N-methylmorpholine / dimethylformamide / Ambient temperature

With 4-methyl-morpholine; In N,N-dimethyl-formamide;
DOI:10.1016/S0040-4020(01)98817-9

Reference yield:

: 209113-00-8
N-Cbs-L-Ala-OPiv

: Asp(OtBu).Ser(tBu).Thr(tBu).Leu_.OtBu p-toluenesulphonate

: 95525-64-7
Z_.Ala_.Asp(OtBu).Ser(tBu).Thr(tBu).Leu(OtBu)

Guidance literature:: With 4-methyl-morpholine; In N,N-dimethyl-formamide; Yield given; Ambient temperature;
DOI:10.1016/S0040-4020(01)98817-9