2-Naphthalenecarboxylic acid, 5,6-dihydro-7-(1H-imidazol-1-yl)-, ethyl ester

Base Information

Chemical Name:2-Naphthalenecarboxylic acid, 5,6-dihydro-7-(1H-imidazol-1-yl)-, ethyl ester
CAS No.:89781-86-2
Molecular Formula:C₁₆H₁₆N₂O₂
Molecular Weight:268.315
Hs Code.:
DSSTox Substance ID:DTXSID20237896
Nikkaji Number:J419.954E
Wikidata:Q83120160

Synonyms:89781-86-2;BRN 4755035;Ethyl 7-(1H-imidazol-1-yl)-5,6-dihydro-2-naphthalenecarboxylate;2-Naphthalenecarboxylic acid, 5,6-dihydro-7-(1H-imidazol-1-yl)-, ethyl ester;Ethyl 7-(1H-imidazol-1-yl)-5,6-dihydronaphthalene-2-carboxylate;SCHEMBL7444886;DTXSID20237896;HUZBRJVXYZZTRG-UHFFFAOYSA-N;LS-94512;1,2-dihydro-3-(1-imidazolyl)-6-ethoxycarbonyl-naphthalene;5,6-Dihydro-7-(1H-imidazol-1-yl)naphthalene-2-carboxylic acid ethyl ester

Suppliers and Price of 2-Naphthalenecarboxylic acid, 5,6-dihydro-7-(1H-imidazol-1-yl)-, ethyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of 2-Naphthalenecarboxylic acid, 5,6-dihydro-7-(1H-imidazol-1-yl)-, ethyl ester

Chemical Property:

Vapor Pressure:1.31E-08mmHg at 25°C
Boiling Point:459°Cat760mmHg
Flash Point:231.4°C
Density:1.2g/cm³
XLogP3:2.7
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:4
Exact Mass:268.121177757
Heavy Atom Count:20
Complexity:394

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC(=O)C1=CC2=C(CCC(=C2)N3C=CN=C3)C=C1

Technology Process of 2-Naphthalenecarboxylic acid, 5,6-dihydro-7-(1H-imidazol-1-yl)-, ethyl ester

There total 4 articles about 2-Naphthalenecarboxylic acid, 5,6-dihydro-7-(1H-imidazol-1-yl)-, ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.0%

: 64-17-5
ethanol

: 89781-55-5
5,6-dihydro-7-(1H-imidazol-1-yl)-2-naphthalenecarboxylic acid

: 89781-86-2
ethyl 5,6-dihydro-7-(1H-imidazol-1-yl)-2-naphthalene carboxylate

Guidance literature:: With thionyl chloride; for 24h; Heating;
DOI:10.1016/0223-5234(91)90103-T

Reference yield:

: CHCl₃:CH₃ OH

: 89781-55-5
5,6-dihydro-7-(1H-imidazol-1-yl)-2-naphthalenecarboxylic acid

: 89781-86-2
ethyl 5,6-dihydro-7-(1H-imidazol-1-yl)-2-naphthalene carboxylate

Guidance literature:: With thionyl chloride; In ethanol;

Reference yield:

: 85929-03-9
2-(1-imidazolyl)-1,2,3,4-tetrahydro-7-carboxy-1-naphthalenol

: 89781-86-2
ethyl 5,6-dihydro-7-(1H-imidazol-1-yl)-2-naphthalene carboxylate

Guidance literature:: Multi-step reaction with 2 steps

1: 71 percent / conc. H₂SO₄ / acetic acid / 4 h / 100 °C

2: 72 percent / SOCl₂ / 24 h / Heating

With thionyl chloride; sulfuric acid; In acetic acid;
DOI:10.1016/0223-5234(91)90103-T