4-(3-Chlorophenyl)-1,2,3,6-tetrahydropyridine

Base Information

Chemical Name:4-(3-Chlorophenyl)-1,2,3,6-tetrahydropyridine
CAS No.:95884-51-8
Molecular Formula:C11H12ClN
Molecular Weight:193.676
Hs Code.:
DSSTox Substance ID:DTXSID70442054
Nikkaji Number:J1.211.868F
Wikidata:Q82259119
ChEMBL ID:CHEMBL2021657
Mol file:95884-51-8.mol

Synonyms:4-(3-chlorophenyl)-1,2,3,6-tetrahydropyridine;95884-51-8;Pyridine, 4-(3-chlorophenyl)-1,2,3,6-tetrahydro-;CHEMBL2011567;SCHEMBL4510248;CHEMBL2021657;DTXSID70442054;GUMKLSMBRGGWAH-UHFFFAOYSA-N;BDBM50379822;AKOS000205415;CS-0238332;EN300-193213;F70215;1,2,3,6-Tetrahydro-4-(3-chlorophenyl)pyridine;4-(3-chlorophenyl)-1,2,3,6-tetrahydro-pyridine;4-(3-Chloro-phenyl)-1,2,3,6-tetrahydro-pyridine;4-(3-chlorophenyl)-1,2, 3,6-tetrahydro-pyridine

Suppliers and Price of 4-(3-Chlorophenyl)-1,2,3,6-tetrahydropyridine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 4 raw suppliers

Chemical Property of 4-(3-Chlorophenyl)-1,2,3,6-tetrahydropyridine

Chemical Property:

XLogP3:2.6
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:1
Exact Mass:193.0658271
Heavy Atom Count:13
Complexity:200

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CNCC=C1C2=CC(=CC=C2)Cl

Technology Process of 4-(3-Chlorophenyl)-1,2,3,6-tetrahydropyridine

There total 1 articles about 4-(3-Chlorophenyl)-1,2,3,6-tetrahydropyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 358722-20-0
tert-butyl 4-(3-chlorophenyl)-5,6-dihydropyridine-1(2H)-carboxylate

: 95884-51-8
4-(3-chlorophenyl)-1,2,3,6-tetrahydropyridine

Guidance literature:: With trifluoroacetic acid; In dichloromethane; at 0 - 20 ℃;
DOI:10.1016/j.bmcl.2008.08.020

Reference yield: 58.0%

: 3-(4-chlorobutyl)-3-ethyl-5-fluoro-1,3-dihydro-2H-indol-2-one

: 95884-51-8
4-(3-chlorophenyl)-1,2,3,6-tetrahydropyridine

: 3-{4-[4-(3-chlorophenyl)-3,6-dihydropyridin-1(2H)-yl]butyl}-3-ethyl-5-fluoro-1,3-dihydro-2H-indol-2-one

Guidance literature:: With sodium carbonate; at 180 ℃; for 1h;
DOI:10.1021/jm200547z

Reference yield: 57.0%

: 4-(6-fluoro-2-oxo-2,3-dihydro-1H-indol-3-yl)butyl methanesulfonate

: 95884-51-8
4-(3-chlorophenyl)-1,2,3,6-tetrahydropyridine

: 3-{4-[4-(3-chlorophenyl)-3,6-dihydropyridin-1(2H)-yl]butyl}-6-fluoro-1,3-dihydro-2H-indol-2-one hydrochloride

Guidance literature:: 4-(6-fluoro-2-oxo-2,3-dihydro-1H-indol-3-yl)butyl methanesulfonate; 4-(3-chlorophenyl)-1,2,3,6-tetrahydropyridine; With sodium carbonate; at 120 ℃; for 1h;

With hydrogenchloride; In diethyl ether;
DOI:10.1021/jm200547z