3-Amino-2,3,6-trideoxy-2-fluorogalactose

Base Information

Chemical Name:3-Amino-2,3,6-trideoxy-2-fluorogalactose
CAS No.:99773-72-5
Molecular Formula:C₇H₁₄FNO₃
Molecular Weight:179.191
Hs Code.:
Mol file:99773-72-5.mol

Synonyms:2-fluoro-D-ristosamine;2-fluorodaunosamine;3-amino-2,3,6-trideoxy-2-fluorogalactose

Suppliers and Price of 3-Amino-2,3,6-trideoxy-2-fluorogalactose

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 4 raw suppliers

Chemical Property of 3-Amino-2,3,6-trideoxy-2-fluorogalactose

Chemical Property:

Vapor Pressure:0.000944mmHg at 25°C
Melting Point:177 - 178 °C (hexane)
Boiling Point:269.8°Cat760mmHg
Flash Point:116.9°C
PSA：64.71000
Density:1.2g/cm³
LogP:0.10420
XLogP3:-0.8
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:1
Exact Mass:179.09577147
Heavy Atom Count:12
Complexity:158

Purity/Quality:: 99%+ ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC1C(C(C(C(O1)OC)F)N)O
Isomeric SMILES:C[C@H]1[C@H]([C@H]([C@@H]([C@H](O1)OC)F)N)O

Technology Process of 3-Amino-2,3,6-trideoxy-2-fluorogalactose

There total 5 articles about 3-Amino-2,3,6-trideoxy-2-fluorogalactose which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.3%

: 95239-49-9
methyl 3-benzamido-4-O-benzoyl-2,3,6-trideoxy-2-fluoro-β-L-galactopyranoside

: 99773-72-5
methyl (S)-2-fluoro-β-daunosaminide

Guidance literature:: With sodium hydroxide; In 2-methoxy-ethanol; water; for 21h; Heating; the base was added in two portions;
DOI:10.1016/0008-6215(85)85123-5

Reference yield:

: 99827-93-7
methyl 2-benzamido-4,6-O-benzylidene-2-deoxy-3-O-(methylsulfonyl)-α-D-glucopyranoside

: 99773-72-5
methyl (S)-2-fluoro-β-daunosaminide

Guidance literature:: Multi-step reaction with 5 steps

1: 63 percent / tetrabutylammonium fluoride / acetonitrile / 24 h / 80 °C / to the exclusion of moisture

2: 82.4 percent / N-bromosuccinimide, barium carbonate / CCl₄ / 3 h / Heating

3: 93 percent / silver fluoride / 4-(dimethylamino)pyridine / pyridine / 6 h / Ambient temperature; in the dark

4: 62 percent / H₂ / Kuhn catalyst / methanol / 2 h / Ambient temperature

5: 85.3 percent / sodium hydroxide / 2-methoxy-ethanol; H₂O / 21 h / Heating; the base was added in two portions

With sodium hydroxide; N-Bromosuccinimide; tetrabutyl ammonium fluoride; hydrogen; silver fluoride; barium carbonate; dmap; Kuhn catalyst; In pyridine; methanol; tetrachloromethane; 2-methoxy-ethanol; water; acetonitrile;
DOI:10.1016/0008-6215(85)85123-5

Reference yield:

: 74801-07-3
methyl 3-benzamido-4,6-O-benzylidene-2,3-dideoxy-2-fluoro-α-D-altropyranoside

: 99773-72-5
methyl (S)-2-fluoro-β-daunosaminide

Guidance literature:: Multi-step reaction with 4 steps

1: 82.4 percent / N-bromosuccinimide, barium carbonate / CCl₄ / 3 h / Heating

2: 93 percent / silver fluoride / 4-(dimethylamino)pyridine / pyridine / 6 h / Ambient temperature; in the dark

3: 62 percent / H₂ / Kuhn catalyst / methanol / 2 h / Ambient temperature

4: 85.3 percent / sodium hydroxide / 2-methoxy-ethanol; H₂O / 21 h / Heating; the base was added in two portions

With sodium hydroxide; N-Bromosuccinimide; hydrogen; silver fluoride; barium carbonate; dmap; Kuhn catalyst; In pyridine; methanol; tetrachloromethane; 2-methoxy-ethanol; water;
DOI:10.1016/0008-6215(85)85123-5