3-Methoxy-alpha-methyl-L-tyrosine

Base Information

Chemical Name:3-Methoxy-alpha-methyl-L-tyrosine
CAS No.:6739-31-7
Molecular Formula:C₁₁H₁₅NO₄
Molecular Weight:225.244
Hs Code.:
European Community (EC) Number:229-797-5
UNII:87SI2AOH39
DSSTox Substance ID:DTXSID80986671
Nikkaji Number:J76.593G
Wikidata:Q27269841
ChEMBL ID:CHEMBL3544652
Mol file:6739-31-7.mol

Synonyms:3-O-methyl-methyldopa;3-O-methylmethyldopa

Suppliers and Price of 3-Methoxy-alpha-methyl-L-tyrosine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
3-Methoxy-α-methyl-L-tyrosine
50mg
$ 1260.00

Sigma-Aldrich
3-O-Methylmethyldopa United States Pharmacopeia (USP) Reference Standard
50mg
$ 1160.00

Medical Isotopes, Inc.
3-Methoxy-α-methyl-L-tyrosine
5 mg
$ 650.00

Total 8 raw suppliers

Chemical Property of 3-Methoxy-alpha-methyl-L-tyrosine

Chemical Property:

Melting Point:310 °C
Boiling Point:407.8±45.0 °C(Predicted)
PKA:2.28±0.26(Predicted)
Flash Point:200.4oC
PSA：92.78000
Density:1.279±0.06 g/cm3(Predicted)
LogP:1.44560
XLogP3:-2.2
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:4
Exact Mass:225.10010796
Heavy Atom Count:16
Complexity:258

Purity/Quality:

99% ^*data from raw suppliers

3-Methoxy-α-methyl-L-tyrosine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:Xn
Statements: 22-36
Safety Statements: 26

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(CC1=CC(=C(C=C1)O)OC)(C(=O)O)N
Isomeric SMILES:C[C@](CC1=CC(=C(C=C1)O)OC)(C(=O)O)N
Uses 3-Methoxy-α-methyl-L-tyrosine is a metabolite of methylenedioxyamphetamine (M303965). 3-Methoxy-α-methyl-L-tyrosine (Methyldopa EP Impurity A) is a metabolite of methylenedioxyamphetamine (M303965).

Technology Process of 3-Methoxy-alpha-methyl-L-tyrosine

There total 3 articles about 3-Methoxy-alpha-methyl-L-tyrosine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 498-00-0
4-hydroxymethyl-2-methoxyphenol

: 15073-80-0,6739-31-7
3-0-Methyldopa

Guidance literature:: Multi-step reaction with 2 steps

1: 68 percent / tetrabutylammonium chloride, potassium fluoride dihydrate / toluene / 30 h / Heating

2: 2.) H₂ / 1.) Raney-Ni, 2.) PtO₂ / 1.) MeOH, reflux, 2.) MeOH

With potassium fluoride; tetrabutyl-ammonium chloride; hydrogen; platinum(IV) oxide; nickel; In toluene;
DOI:10.1002/ardp.19823150515

Reference yield:

: 82408-62-6
2-Nitro-2-(4-hydroxy-3-methoxybenzyl)propionsaeureethylester

: 15073-80-0,6739-31-7
3-0-Methyldopa

Guidance literature:: With hydrogen; platinum(IV) oxide; nickel; Yield given. Multistep reaction; 1.) MeOH, reflux, 2.) MeOH;
DOI:10.1002/ardp.19823150515