Cyclopenin

Base Information

Chemical Name:Cyclopenin
CAS No.:20007-87-8
Molecular Formula:C₁₇H₁₄N₂O₃
Molecular Weight:294.31
Hs Code.:
NSC Number:114538
Wikidata:Q77564000
Metabolomics Workbench ID:104002

Synonyms:cyclopenin

Suppliers and Price of Cyclopenin

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
Cyclopenin
5mg
$ 453.00

Usbiological
Cyclopenin
1mg
$ 329.00

Cayman Chemical
Cyclopenin ≥99%
25mg
$ 823.00

Cayman Chemical
Cyclopenin ≥99%
5mg
$ 235.00

Total 6 raw suppliers

Chemical Property of Cyclopenin

Chemical Property:

Boiling Point:572.5°Cat760mmHg
Flash Point:300.1°C
PSA：61.94000
Density:1.4g/cm³
LogP:2.25440
XLogP3:1.5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:294.10044231
Heavy Atom Count:22
Complexity:488

Purity/Quality:

99% ^*data from raw suppliers

Cyclopenin ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CN1C(=O)C2=CC=CC=C2NC(=O)C13C(O3)C4=CC=CC=C4
Description Cyclopenin is an inhibitor of acetylcholinesterase (AChE; IC50 = 2.04 μM for human recombinant AChE) that is produced by Penicillium. It exhibits greater than 2,000-fold selectivity over recombinant equine butyrylcholinesterase with an IC50 value greater than 4,080 μM. Cyclopenin also has antibacterial activity against E. coli and M. pyogenes.

Technology Process of Cyclopenin

There total 9 articles about Cyclopenin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 36.0%

: 19113-24-7
(Z)-3-benzylidene-4-methyl-3,4-dihydro-1H-benzo[e][1,4]diazepine-2,5-dione

: 19357-57-4,19553-26-5,20007-87-8,25273-38-5
4-methyl-3'-phenylspiro[benzo[e][1,4]diazepine-3,2'-oxirane]-2,5(1H,4H)-dione

Guidance literature:: With sodium hydrogencarbonate; 3-chloro-benzenecarboperoxoic acid; In dichloromethane; for 72h; Reflux;
DOI:10.1002/anie.201710567

Reference yield:

: 31965-37-4
3-benzylidene-4-methyl-3,4-dihydro-1H-benzo[e][1,4]diazepine-2,5-dione

: 19357-57-4,19553-26-5,20007-87-8,25273-38-5
(-)-cyclopenin

Guidance literature:: With α-keto-glutarate (α-KG)-dependent iron(Fe/α-KG) enzyme AsqJ; oxygen; α-ketoglutarate; iron(II); In aq. buffer; at 6 ℃; Enzymatic reaction;
DOI:10.1021/jacs.6b05400