viridicatin

Base Information

Chemical Name:viridicatin
CAS No.:129-24-8
Molecular Formula:C15H11 N O2
Molecular Weight:237.258
Hs Code.:2933499090
NSC Number:656625
UNII:45493KS618
DSSTox Substance ID:DTXSID10156022
Nikkaji Number:J5.422D
Wikidata:Q27258806
Metabolomics Workbench ID:164728
ChEMBL ID:CHEMBL2386742
Mol file:129-24-8.mol

Synonyms:Carbostyril,3-hydroxy-4-phenyl- (7CI,8CI); 2,3-Dihydroxy-4-phenylquinoline;2,6-Dihydroxy-4-phenylquinoline; 3-Hydroxy-4-phenyl-2(1H)-quinolinone;3-Hydroxy-4-phenyl-2-quinolone; 3-Hydroxy-4-phenylcarbostyril;3-Hydroxy-4-phenylquinolin-2-one; NSC 656625; Viridicatin; Viridicatine

Suppliers and Price of viridicatin

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
Viridicatin
1mg
$ 426.00

TRC
Viridicatin
25mg
$ 475.00

Cayman Chemical
Viridicatin ≥99%
5mg
$ 470.00

Cayman Chemical
Viridicatin ≥99%
1mg
$ 99.00

American Custom Chemicals Corporation
VIRIDICATIN 95.00%
5MG
$ 496.84

AK Scientific
Viridicatin
1mg
$ 233.00

Total 9 raw suppliers

Chemical Property of viridicatin

Chemical Property:

Vapor Pressure:6.79E-10mmHg at 25°C
Melting Point:268°
Boiling Point:476.7°Cat760mmHg
Flash Point:242.1°C
PSA：53.35000
Density:1.323g/cm³
LogP:3.31300
XLogP3:2.4
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:237.078978594
Heavy Atom Count:18
Complexity:369

Purity/Quality:

98%min ^*data from raw suppliers

Viridicatin ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)C2=C(C(=O)NC3=CC=CC=C32)O
Uses Viridicatin is a fungal metabolite produced by several species of Penicillium and formed by the rearrangement of the benzodiazepine, cyclopenin. Viridicatin exhibits potent selective activity against Mycobacterium tuberculosis, but is inactive against most other bacteria. Viridicatin is a?Penicillium?metabolite active against?Mycobacterium tuberculosis. Isolated from deep-sea Penicillium griseofulvum alleviates anaphylaxis and has anti-?allergic properties.

Technology Process of viridicatin

There total 27 articles about viridicatin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

: 2,2-dichloro-N-(4-methoxybenzyl)-N-phenylacetamide

: 100-52-7
benzaldehyde

: 129-24-8
4-phenyl-3-hydroxyquinolin-2(1H)-one

: 1134192-59-8
3-hydroxy-1-(4-methoxybenzyl)-4-phenylquinolin-2(1H)-one

Guidance literature:: 2,2-dichloro-N-(4-methoxybenzyl)-N-phenylacetamide; benzaldehyde; With potassium tert-butylate; In toluene; at -45 - 20 ℃; for 6.5h;

With hydrogenchloride; In toluene; Cooling with ice;
DOI:10.1021/acs.joc.1c01592

Reference yield: 86.0%

: 91-56-5,1186480-61-4,84788-92-1
indole-2,3-dione

: 100-52-7
benzaldehyde

: 129-24-8
4-phenyl-3-hydroxyquinolin-2(1H)-one

Guidance literature:: With potassium carbonate; toluene-4-sulfonic acid hydrazide; In ethanol; at 80 ℃; for 8h; Reagent/catalyst; Solvent; Temperature; regioselective reaction;
DOI:10.1021/acs.orglett.8b01417