Benzene, 1-chloro-4-(2,2-diphenylcyclopropyl)-

Base Information

• Chemical Name: Benzene, 1-chloro-4-(2,2-diphenylcyclopropyl)-
• CAS No.: 96010-04-7
• Molecular Formula: C21H17Cl
• Molecular Weight: 304.81300
• DSSTox Substance ID: DTXSID10394583
• Mol file: 96010-04-7.mol

Synonyms:Benzene, 1-chloro-4-(2,2-diphenylcyclopropyl)-;96010-04-7;DTXSID10394583

Chemical Property of Benzene, 1-chloro-4-(2,2-diphenylcyclopropyl)-

Chemical Property:

• Boiling Point: 393.6±41.0 °C(Predicted)
• PSA: 0.00000
• Density: 1.189±0.06 g/cm3(Predicted)
• LogP: 5.81360
• XLogP3: 6.3
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 0
• Rotatable Bond Count: 3
• Exact Mass: 304.1018782
• Heavy Atom Count: 22
• Complexity: 338

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: C1C(C1(C2=CC=CC=C2)C3=CC=CC=C3)C4=CC=C(C=C4)Cl

Technology Process of Benzene, 1-chloro-4-(2,2-diphenylcyclopropyl)-

There total 7 articles about Benzene, 1-chloro-4-(2,2-diphenylcyclopropyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 73.0%

4-vinylbenzyl chloride (1073-67-2,24991-47-7) + benzophenone hydrazone (5350-57-2) → (2-(4-chlorophenyl)cyclopropane-1,1-diyl)dibenzene (96010-04-7)

Guidance literature:

With iodosylbenzene; nickel(II) hydroxide; at 80 ℃; for 0.666667h;

DOI:10.1039/c5nj02378e

Reference yield: 67.0%

bromochlorobenzene (106-39-8) + 1-bromo-2,2-diphenyl cyclopropane (32812-52-5) → (2-(4-chlorophenyl)cyclopropane-1,1-diyl)dibenzene (96010-04-7)

Guidance literature:

1-bromo-2,2-diphenyl cyclopropane; With TurboGrignard; In tetrahydrofuran; 1,4-dioxane; at 25 ℃; for 48h;

With zinc(II) chloride; In tetrahydrofuran; 1,4-dioxane;

bromochlorobenzene; With Pd(OAc)2*1.5S-Phos; In tetrahydrofuran; 1,4-dioxane; stereoselective reaction;

DOI:10.1055/s-0028-1087487

Reference yield:

C70H28F20N4Os + 4-vinylbenzyl chloride (1073-67-2,24991-47-7) → (2-(4-chlorophenyl)cyclopropane-1,1-diyl)dibenzene (96010-04-7)

Guidance literature:

at 80 ℃; for 10h;

DOI:10.1021/ja003184q

upstream raw materials:

4-vinylbenzyl chloride

diazodiphenylmethane

benzophenone tosylhydrasone sodium salt

3-Chlorostyrene