(2-Bromo-1-phenylcyclopropyl)benzene

Base Information

• Chemical Name: (2-Bromo-1-phenylcyclopropyl)benzene
• CAS No.: 32812-52-5
• Molecular Formula: C15H13Br
• Molecular Weight: 273.172
• NSC Number: 135740
• DSSTox Substance ID: DTXSID90300263
• Nikkaji Number: J1.702.158C
• Mol file: 32812-52-5.mol

Synonyms:(2-Bromo-1-phenylcyclopropyl)benzene;32812-52-5;NSC135740;SCHEMBL5076521;DTXSID90300263;1-bromo-2,2-diphenylcyclopropane;1-bromo-2,2-diphen-ylcyclopropane;1-bromo-2,2-diphenyl-cyclopropane;NSC-135740;(2-Bromo-1-phenylcyclopropyl)benzene #;Benzene, 1,1'-(bromocyclopropylidene)bis-

Chemical Property of (2-Bromo-1-phenylcyclopropyl)benzene

Chemical Property:

• Boiling Point: 343.7°Cat760mmHg
• Flash Point: 146°C
• Density: 1.405g/cm³
• XLogP3: 4.6
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 0
• Rotatable Bond Count: 2
• Exact Mass: 272.02006
• Heavy Atom Count: 16
• Complexity: 218

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1C(C1(C2=CC=CC=C2)C3=CC=CC=C3)Br

Technology Process of (2-Bromo-1-phenylcyclopropyl)benzene

There total 7 articles about (2-Bromo-1-phenylcyclopropyl)benzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 54.0%

1,1-dibromo-2,2-diphenylcyclopropane (17343-74-7) → 1,1-diphenyl-1,2-propadiene (14251-57-1) + 1-bromo-2,2-diphenyl cyclopropane (32812-52-5)

Guidance literature:

With ethanol; phenol; salcomine; In N,N-dimethyl-formamide; Electrochemical reaction;

DOI:10.1023/A:1024456510964

Reference yield:

1,1-Diphenylethylene (530-48-3) → 1-bromo-2,2-diphenyl cyclopropane (32812-52-5)

Guidance literature:

Multi-step reaction with 2 steps

1: 84 percent / NaOH, triethylbenzylammonium chloride / CH₂Cl₂; ethanol / 16 h / 25 °C

2: 60 percent / tributylstannane / benzene / 35 - 40 °C

With sodium hydroxide; N-benzyl-N,N,N-triethylammonium chloride; tri-n-butyl-tin hydride; In ethanol; dichloromethane; benzene;

Reference yield:

benzophenone (119-61-9) → 1-bromo-2,2-diphenyl cyclopropane (32812-52-5)

Guidance literature:

Multi-step reaction with 3 steps

1: n-butyllithium / tetrahydrofuran / 48 h / 0 - 20 °C

2: sodium hydroxide / water; dichloromethane / 24 h / 25 °C

3: titanium(IV) isopropylate; ethylmagnesium bromide / tetrahydrofuran / 4 h / 25 °C

With titanium(IV) isopropylate; n-butyllithium; ethylmagnesium bromide; sodium hydroxide; In tetrahydrofuran; dichloromethane; water;

DOI:10.1021/acs.orglett.5b01542

upstream raw materials:

1,1-dibromo-2,2-diphenylcyclopropane

1,1-Diphenylethylene

benzophenone

bromobenzene

Downstream raw materials:

1-methyl-2,2-diphenylcyclopropane

(2-(4-chlorophenyl)cyclopropane-1,1-diyl)dibenzene

C₁₆H₁₆S

C₂₄H₂₂O₂