1-(2-Hydroxyethyl)-4,6-diphenylpyridine-2(1H)-thione

Base Information

• Chemical Name: 1-(2-Hydroxyethyl)-4,6-diphenylpyridine-2(1H)-thione
• CAS No.: 96185-26-1
• Molecular Formula: C19H17NOS
• Molecular Weight: 307.416
• DSSTox Substance ID: DTXSID70539872
• Nikkaji Number: J980.255J
• Wikidata: Q82415687
• Mol file: 96185-26-1.mol

Synonyms:1-(2-Hydroxyethyl)-4,6-diphenylpyridine-2(1H)-thione;96185-26-1;SCHEMBL3035340;DTXSID70539872

Chemical Property of 1-(2-Hydroxyethyl)-4,6-diphenylpyridine-2(1H)-thione

Chemical Property:

• XLogP3: 3.1
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 4
• Exact Mass: 307.10308534
• Heavy Atom Count: 22
• Complexity: 456

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: C1=CC=C(C=C1)C2=CC(=S)N(C(=C2)C3=CC=CC=C3)CCO

Technology Process of 1-(2-Hydroxyethyl)-4,6-diphenylpyridine-2(1H)-thione

There total 1 articles about 1-(2-Hydroxyethyl)-4,6-diphenylpyridine-2(1H)-thione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

4,6-diphenyl-2H-pyran-2-thione (26479-00-5) + ethanolamine (141-43-5) → 1-(2-hydroxyethyl)-4,6-diphenylpyridin-2-thione (96185-26-1)

Guidance literature:

In methanol; for 5h; Heating;

DOI:10.1016/S0040-4039(00)61913-5

Reference yield: 89.0%

1-(2-hydroxyethyl)-4,6-diphenylpyridin-2-thione (96185-26-1) → 2,3-dihydro-5,7-diphenyloxazolo(3,2-a)pyridinium iodide (96185-27-2) + (4-chlorophenyl)methanethiol (6258-66-8)

Guidance literature:

With 1-chloro-4-(iodomethyl)benzene; In benzene; at 20 ℃; for 3h; various alkyl and aryl halogenides;

DOI:10.1016/S0040-4039(00)61913-5

Reference yield: 80.0%

1-(2-hydroxyethyl)-4,6-diphenylpyridin-2-thione (96185-26-1) + 2,6-Dichloro-benzoic acid 4-bromomethyl-1,1,3-trioxo-1,3-dihydro-1λ6-benzo[d]isothiazol-2-ylmethyl ester (211358-34-8) → 2-[2-(2,6-Dichloro-benzoyloxymethyl)-1,1,3-trioxo-2,3-dihydro-1H-1λ6-benzo[d]isothiazol-4-ylmethylsulfanyl]-1-(2-hydroxy-ethyl)-4,6-diphenyl-pyridinium; bromide

Guidance literature:

In benzene; Ambient temperature;

DOI:10.1016/S0040-4039(98)01074-0

upstream raw materials:

4,6-diphenyl-2H-pyran-2-thione

ethanolamine

Downstream raw materials:

4-methylbenzylthiol

2,3-dihydro-5,7-diphenyloxazolo(3,2-a)pyridinium iodide

(4-chlorophenyl)methanethiol