2-Methyl-8-phenoxyimidazo[1,2-a]pyridine

Base Information

Chemical Name:2-Methyl-8-phenoxyimidazo[1,2-a]pyridine
CAS No.:96428-91-0
Molecular Formula:C14H12N2O
Molecular Weight:224.262
Hs Code.:
DSSTox Substance ID:DTXSID301277257

Synonyms:2-methyl-8-phenoxyimidazo[1,2-a]pyridine;96428-91-0;SCHEMBL11070005;NSINJVIYMIPUMD-UHFFFAOYSA-N;DTXSID301277257

Suppliers and Price of 2-Methyl-8-phenoxyimidazo[1,2-a]pyridine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 0 raw suppliers

Chemical Property of 2-Methyl-8-phenoxyimidazo[1,2-a]pyridine

Chemical Property:

XLogP3:3.7
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:224.094963011
Heavy Atom Count:17
Complexity:253

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC1=CN2C=CC=C(C2=N1)OC3=CC=CC=C3

Technology Process of 2-Methyl-8-phenoxyimidazo[1,2-a]pyridine

There total 2 articles about 2-Methyl-8-phenoxyimidazo[1,2-a]pyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 16867-03-1
2-amino-3-hydroxypyridine

: 96428-91-0
2-methyl-8-phenoxyimidazo<1,2-a>pyridine

Guidance literature:: Multi-step reaction with 2 steps

1: 20 percent / ethanol / 20 h / Heating

2: 1.) 86 percent potassium hydroxide, 2.) copper powder / 1.) methanol, N-methylpyrrolidone, 0.5 h, 2.) reflux, 4 h

With potassium hydroxide; copper; In ethanol;
DOI:10.1021/jm00145a006

Reference yield:

: 108-86-1,52753-63-6
bromobenzene

: 79707-11-2
8-hydroxy-2-methyl-imidazo[1,2-a]pyridine

: 96428-91-0
2-methyl-8-phenoxyimidazo<1,2-a>pyridine

Guidance literature:: With potassium hydroxide; copper; Yield given. Multistep reaction; 1.) methanol, N-methylpyrrolidone, 0.5 h, 2.) reflux, 4 h;
DOI:10.1021/jm00145a006

Reference yield: 97.0%

: 29682-15-3
methyl 5-bromopicolinate

: 96428-91-0
2-methyl-8-phenoxyimidazo<1,2-a>pyridine

: methyl 5-(2-methyl-8-phenoxyimidazo[1,2-a]pyridin-3-yl)pyridine-2-carboxylate

Guidance literature:: With palladium diacetate; caesium carbonate; triphenylphosphine; In 1,4-dioxane; for 48h; Reflux;
DOI:10.1016/j.bmc.2019.115132