6-O-methyl-alpha-D-galactopyranose

Base Information

• Chemical Name: 6-O-methyl-alpha-D-galactopyranose
• CAS No.: 31505-26-7
• Molecular Formula: C7H14 O6
• Molecular Weight: 194.185
• Hs Code.: 2932999099
• Mol file: 31505-26-7.mol

Synonyms:Galactopyranose,6-O-methyl- (6CI); Galactopyranose, 6-O-methyl-, a-D- (8CI); 6-O-Methyl-a-D-galactopyranose

Chemical Property of 6-O-methyl-alpha-D-galactopyranose

Chemical Property:

• Melting Point: 122 °C(Solv: methanol (67-56-1); ethyl ether (60-29-7))
• Boiling Point: 366.3°Cat760mmHg
• PKA: 12.12±0.70(Predicted)
• Flash Point: 175.3°C
• PSA: 99.38000
• Density: 1.5g/cm³
• LogP: -2.56730

Purity/Quality:

99% ^*data from raw suppliers

6-O-METHYL-ALPHA-D-GALACTOPYRANOSE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 6-O-methyl-alpha-D-galactopyranose

There total 14 articles about 6-O-methyl-alpha-D-galactopyranose which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

C35H38O6 (1362023-07-1) → 6-O-methyl-D-mannopyranose (10287-49-7,14199-58-7,24436-14-4,31505-26-7,31505-27-8,31505-28-9,31505-29-0,87936-86-5,87936-87-6,27552-12-1)

Guidance literature:

With 20 % Pd(OH)2/C; hydrogen; acetic acid; In methanol; for 48h; under 60.006 Torr;

DOI:10.1039/c2cc17393j

Reference yield: 39.0%

methoxyacetaldehyde (10312-83-1) + Glycolaldehyde (141-46-8) → 6-O-Methyl-D-glucose (10287-49-7,14199-58-7,24436-14-4,27552-12-1,31505-26-7,31505-27-8,31505-28-9,31505-29-0,87936-86-5,87936-87-6)

Guidance literature:

With Escherichia coli D-fructose-6-phosphate aldolase A₁₂₉T/A₁₆₅G/S₁₆₆G mutant; for 24h; Time; stereoselective reaction; Enzymatic reaction;

DOI:10.1038/nchem.2321

Reference yield: 4.0%

methoxyacetaldehyde (10312-83-1) + Glycolaldehyde (141-46-8) → 6-O-Methyl-D-glucose (10287-49-7,14199-58-7,24436-14-4,27552-12-1,31505-26-7,31505-27-8,31505-28-9,31505-29-0,87936-86-5,87936-87-6) + C7H14O6

Guidance literature:

methoxyacetaldehyde; Glycolaldehyde; With Escherichia coli D-fructose-6-phosphate aldolase A₁₂₉T/A₁₆₅G mutant; Enzymatic reaction;

With Escherichia coli D-fructose-6-phosphate aldolase A₁₂₉T mutant; stereoselective reaction; Enzymatic reaction;

DOI:10.1038/nchem.2321

upstream raw materials:

Benzyl 2,3,4-tri-O-benzyl-α-D-galactopyranosid

O¹,O²;O³,O⁴-diisopropylidene-O⁶-methyl-α-D-galactopyranose

1,2:3,4-di-O-isopropylidene-α-D-galactopyranose

methoxyacetaldehyde

Downstream raw materials:

2-O-acetyl-3,4-di-O-benzyl-6-O-methyl-α-D-galactopyranosyl bromide

3,4-di-O-benzyl-1,2-O-(1-methoxyethylidene)-6-O-methyl-α-D-galactopyranose

methyl 2-acetamido-3-O-(3,4-di-O-benzyl-6-O-methyl-β-D-galactopyranosyl)-6-O-benzyl-2-deoxy-β-D-glucopyranoside

methyl 2-acetamido-3-O-(2-O-acetyl-3,4-di-O-benzyl-6-O-methyl-β-D-galactopyranosyl)-6-O-benzyl-2-deoxy-β-D-glucopyranoside