3,4-Diphenylcyclobutane-1,2-dicarboxylic acid

Base Information

Chemical Name:3,4-Diphenylcyclobutane-1,2-dicarboxylic acid
CAS No.:4482-52-4
Molecular Formula:C18H16O4
Molecular Weight:296.323
Hs Code.:2917399090
NSC Number:126893,103002
DSSTox Substance ID:DTXSID60963283
Nikkaji Number:J8.738F
Wikipedia:Truxinic acid,Truxinic_acid
Wikidata:Q82945122
Mol file:4482-52-4.mol

Synonyms:4482-52-4;528-34-7;.beta.-Truxinic acid;3,4-diphenylcyclobutane-1,2-dicarboxylic acid;Truxinic acid;1, 3,4-diphenyl-;1,2-Cyclobutanedicarboxylic acid, 3,4-diphenyl-;SCHEMBL3482659;DTXSID60963283;QVNDSQQNODQYJM-UHFFFAOYSA-N;NSC103002;NSC126893;NSC-103002;NSC-126893;3,4-Diphenyl-1,2-cyclobutanedicarboxylic acid #

Suppliers and Price of 3,4-Diphenylcyclobutane-1,2-dicarboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 7 raw suppliers

Chemical Property of 3,4-Diphenylcyclobutane-1,2-dicarboxylic acid

Chemical Property:

Vapor Pressure:1.02E-11mmHg at 25°C
Melting Point:185 - 191 °C
Boiling Point:521.8°Cat760mmHg
Flash Point:283.5°C
PSA：74.60000
Density:1.323g/cm³
LogP:2.96920
XLogP3:2.6
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:4
Exact Mass:296.10485899
Heavy Atom Count:22
Complexity:381

Purity/Quality:: 95% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)C2C(C(C2C(=O)O)C(=O)O)C3=CC=CC=C3

Technology Process of 3,4-Diphenylcyclobutane-1,2-dicarboxylic acid

There total 73 articles about 3,4-Diphenylcyclobutane-1,2-dicarboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

: 478359-02-3
C₃₄H₃₀N₂O₂

: 4482-52-4
3,4-diphenyl-1,2-cyclobutanedicarboxylic acid

: 4,15-diamino[2.2]paracyclophane dihydrochloride

Guidance literature:: With hydrogenchloride; for 24h; Heating;
DOI:10.1002/1099-0690(200207)2002:14<2298::AID-EJOC2298>3.0.CO;2-E

Reference yield: 96.7%

: bis(p-nitrophenyl) β-truxinate

: 4482-52-4
3,4-diphenyl-1,2-cyclobutanedicarboxylic acid

Guidance literature:: With potassium hydroxide; In methanol; for 5h; Heating;
DOI:10.1246/bcsj.58.3399

Reference yield: 62.0%

: 140-10-3
(E)-3-phenylacrylic acid

: 528-34-7,898816-27-8
β-truxinic acid

: 490-16-4,528-32-5,528-33-6,528-34-7,528-35-8,528-36-9,4482-52-4
(1R,2R,3S,4S)-3,4-Diphenyl-cyclobutane-1,2-dicarboxylic acid

Guidance literature:: With (2r,4s,5r)-2,4,5,6-tetrakis(3,6-di-tert-butyl-9H-carbazol-9-yl)isophthalonitrile; In 1,4-dioxane; at 20 ℃; for 36h; diastereoselective reaction; Inert atmosphere; Irradiation;
DOI:10.1039/c9ob02735a