Milverine

Base Information

Chemical Name:Milverine
CAS No.:75437-14-8
Molecular Formula:C₂₀H₂₀N₂
Molecular Weight:288.392
Hs Code.:
UNII:83B517YUVM
DSSTox Substance ID:DTXSID50868359
Nikkaji Number:J22.776E
Wikidata:Q27269420
NCI Thesaurus Code:C66155
ChEMBL ID:CHEMBL2105255
Mol file:75437-14-8.mol

Synonyms:4-((3,3-diphenylpropyl)amino)pyridine;milverine

Suppliers and Price of Milverine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
MILVERINE 95.00%
5MG
$ 503.56

Total 8 raw suppliers

Chemical Property of Milverine

Chemical Property:

Vapor Pressure:1.42E-09mmHg at 25°C
Refractive Index:1.627
Boiling Point:485.3 °C at 760 mmHg
Flash Point:247.3 °C
PSA：24.92000
Density:1.11 g/cm³
LogP:4.78870
XLogP3:4.6
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:6
Exact Mass:288.162648646
Heavy Atom Count:22
Complexity:268

Purity/Quality:

99% ^*data from raw suppliers

MILVERINE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)C(CCNC2=CC=NC=C2)C3=CC=CC=C3

Technology Process of Milverine

There total 6 articles about Milverine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 35.0%

: 504-24-5
4-aminopyridine

: 530-48-3
1,1-Diphenylethylene

: 201230-82-2
carbon monoxide

: 75437-14-8
N-(3,3-diphenylpropyl)-pyridin-4-yl-amine

Guidance literature:: With hydrogen; [Rh(1,3-dimesitylimidazole-2-ylidene)(cod)Cl]; In toluene; at 125 ℃; for 24h;
DOI:10.1002/chem.200601155

Reference yield:

: 75437-13-7
3,3-Diphenyl-N-pyridin-4-yl-propionamide

: 75437-14-8
N-(3,3-diphenylpropyl)-pyridin-4-yl-amine

Guidance literature:: With lithium aluminium tetrahydride; aluminium trichloride; In tetrahydrofuran; at -78 - 25 ℃; for 2h;

Reference yield:

: 530-48-3
1,1-Diphenylethylene

: 75437-14-8
N-(3,3-diphenylpropyl)-pyridin-4-yl-amine

Guidance literature:: Multi-step reaction with 5 steps

1: 85 percent / 2, triphenyl phosphite, H₂ / benzene / 48 h / 80 °C / 76000 Torr

2: 95 percent / NaClO₂, NaHPO₄, 30percent H₂O₂ / H₂O; acetonitrile / 10 °C

3: SOCl₂ / 1 h / Heating

4: pyridine / 2 h / Heating

5: AlCl₃, LiAlH₄ / tetrahydrofuran / 2 h / -78 - 25 °C

With pyridine; triphenyl phosphite; sodium chlorite; lithium aluminium tetrahydride; aluminium trichloride; thionyl chloride; 2-methyl-but-2-ene; di(rhodium)tetracarbonyl dichloride; hydrogen; dihydrogen peroxide; In tetrahydrofuran; water; acetonitrile; benzene;