1-[1-(Benzenesulfonyl)-3-ethyl-1H-pyrrol-2-yl]ethan-1-one

Base Information

Chemical Name:1-[1-(Benzenesulfonyl)-3-ethyl-1H-pyrrol-2-yl]ethan-1-one
CAS No.:97188-34-6
Molecular Formula:C14H15NO3S
Molecular Weight:277.344
Hs Code.:
DSSTox Substance ID:DTXSID20540978
Nikkaji Number:J712.086I
Wikidata:Q82417149

Synonyms:97188-34-6;1-(3-Ethyl-1-(phenylsulfonyl)-1H-pyrrol-2-yl)ethan-1-one;DTXSID20540978;1-[1-(Benzenesulfonyl)-3-ethyl-1H-pyrrol-2-yl]ethan-1-one

Suppliers and Price of 1-[1-(Benzenesulfonyl)-3-ethyl-1H-pyrrol-2-yl]ethan-1-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 1-[1-(Benzenesulfonyl)-3-ethyl-1H-pyrrol-2-yl]ethan-1-one

Chemical Property:

XLogP3:2.7
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:4
Exact Mass:277.07726451
Heavy Atom Count:19
Complexity:421

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCC1=C(N(C=C1)S(=O)(=O)C2=CC=CC=C2)C(=O)C

Technology Process of 1-[1-(Benzenesulfonyl)-3-ethyl-1H-pyrrol-2-yl]ethan-1-one

There total 6 articles about 1-[1-(Benzenesulfonyl)-3-ethyl-1H-pyrrol-2-yl]ethan-1-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 76.0%

: 108-24-7
acetic anhydride

: 97188-23-3
3-ethyl-1-phenylsulfonylpyrrole

: 97188-34-6
2-acetyl-3-ethyl-1-(phenylsulfonyl)pyrrole

Guidance literature:: With aluminium trichloride; at 0 ℃; for 0.5h;
DOI:10.1016/0040-4039(96)00098-6

Reference yield:

: 81453-98-7
3-acetyl-1-(phenylsulfonyl)pyrrole

: 97188-34-6
2-acetyl-3-ethyl-1-(phenylsulfonyl)pyrrole

Guidance literature:: Multi-step reaction with 3 steps

1: 51 percent / KOH, N₂H_4.H₂O / various solvent(s) / 5.5 h / Heating

2: 29 percent / potassium metal / tetrahydrofuran / Ambient temperature

3: 5 percent / AlCl₃ / CH₂Cl₂ / 42 h / Ambient temperature; further catalyst SnCl₄

With potassium hydroxide; potassium; hydrazine hydrate; aluminium trichloride; In tetrahydrofuran; dichloromethane;

Reference yield:

: 98-09-9
benzenesulfonyl chloride

: 97188-34-6
2-acetyl-3-ethyl-1-(phenylsulfonyl)pyrrole

Guidance literature:: Multi-step reaction with 2 steps

1: 29 percent / potassium metal / tetrahydrofuran / Ambient temperature

2: 5 percent / AlCl₃ / CH₂Cl₂ / 42 h / Ambient temperature; further catalyst SnCl₄

With potassium; aluminium trichloride; In tetrahydrofuran; dichloromethane;