Amidapsone

Base Information

• Chemical Name: Amidapsone
• CAS No.: 3569-77-5
• Molecular Formula: C₁₃H₁₃N₃O₃S
• Molecular Weight: 291.331
• Hs Code.: 2924299090
• Mol file: 3569-77-5.mol

Synonyms:Urea,(p-sulfanilylphenyl)- (8CI); Urea, [4-[(4-aminophenyl)sulfonyl]phenyl]- (9CI);(4-Sulfanilylphenyl)urea; (p-Sulfanilylphenyl)urea;1-[4-(4-Sulfanilyl)phenyl]urea; 4-(N-Sulfanilyl)phenylurea;4-Amino-4'-ureidodiphenyl sulfone; Amidapsone; NSC 28120; Sulfacid; Sulfacide;Sulfacide 10A; p-Amino-p'-ureidodiphenyl sulfone

Chemical Property of Amidapsone

Chemical Property:

• Vapor Pressure: 1.4E-11mmHg at 25°C
• Boiling Point: 536.4°Cat760mmHg
• Flash Point: 278.2°C
• PSA: 123.66000
• Density: 1.454g/cm³
• LogP: 4.02750

Purity/Quality:

99% ^*data from raw suppliers

AMIDAPSONE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: Antiviral (for poultry).

Technology Process of Amidapsone

There total 5 articles about Amidapsone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-(4-nitrophenylsulfonyl)aniline (1948-92-1) → sulfacid (3569-77-5)

Guidance literature:

Multi-step reaction with 2 steps

1: 1,4-dioxane; pyridine

2: hydrogenchloride; tin(ll) chloride / Hydrogenation

With 1,4-dioxane; pyridine; hydrogenchloride; tin(ll) chloride;

Reference yield:

[4-(4-nitro-benzenesulfonyl)-phenyl]-urea (33138-27-1) → sulfacid (3569-77-5)

Guidance literature:

With hydrogenchloride; tin(ll) chloride; Hydrogenation;

Reference yield:

4-amino-4'-nitrodiphenyl sulfide (101-59-7) → sulfacid (3569-77-5)

Guidance literature:

Multi-step reaction with 3 steps

1: 1,4-dioxane / Behandeln des Reaktionsprodukts mit wss.Ammoniak

2: dihydrogen peroxide; acetic acid

3: hydrogenchloride; tin(ll) chloride / Hydrogenation

With 1,4-dioxane; hydrogenchloride; dihydrogen peroxide; acetic acid; tin(ll) chloride;

upstream raw materials:

[4-(4-nitro-benzenesulfonyl)-phenyl]-urea

4-amino-4'-nitrodiphenyl sulfide

4-(4-nitrophenylsulfonyl)aniline

[4-(4-nitro-phenylsulfanyl)-phenyl]-urea

Downstream raw materials:

[4-(N-carbamoyl-sulfanilyl)-phenyl]-carbamic acid ethyl ester