5-(4-Fluoro-benzyl)-thiazol-2-ylamine

Base Information

Chemical Name:5-(4-Fluoro-benzyl)-thiazol-2-ylamine
CAS No.:315241-39-5
Molecular Formula:C10H9 F N2 S
Molecular Weight:208.259
Hs Code.:2934100090
DSSTox Substance ID:DTXSID30953510
Wikidata:Q82932388
Mol file:315241-39-5.mol

Synonyms:5-(4-Fluoro-benzyl)-thiazol-2-ylamine;315241-39-5;5-(4-Fluorobenzyl)thiazol-2-amine;5-[(4-fluorophenyl)methyl]-1,3-thiazol-2-amine;MFCD02214714;5-(4-fluorobenzyl)-1,3-thiazol-2-amine;CBMicro_030631;Oprea1_123680;Oprea1_445782;SCHEMBL963712;DTXSID30953510;KIZWUMGELVDUQL-UHFFFAOYSA-N;BBL104240;STK952767;AKOS000122218;WAY-118102;BIM-0030575.P001;2-amino-5-(4-fluorobenzyl)-1,3-thiazole;BB 0241890;EU-0042795;EN300-02539;SR-01000473948;SR-01000473948-1;Z57476086;5-[(4-Fluorophenyl)methyl]-1,3-thiazol-2(3H)-imine;F0862-0126;6047-05-8

Suppliers and Price of 5-(4-Fluoro-benzyl)-thiazol-2-ylamine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
5-[(4-fluorophenyl)methyl]-1,3-thiazol-2-amine
25mg
$ 45.00

SynQuest Laboratories
5-[(4-Fluorophenyl)methyl]-1,3-thiazol-2-amine
250 mg
$ 255.00

Matrix Scientific
5-(4-Fluoro-benzyl)-thiazol-2-ylamine
1g
$ 378.00

Crysdot
5-(4-Fluorobenzyl)thiazol-2-amine 95+%
1g
$ 377.00

Chemenu
5-(4-fluorobenzyl)thiazol-2-amine 95%
1g
$ 356.00

Apolloscientific
5-(4-Fluoro-benzyl)-thiazol-2-ylamine 97%
1g
$ 192.00

Apolloscientific
5-(4-Fluoro-benzyl)-thiazol-2-ylamine 97%
5g
$ 760.00

American Custom Chemicals Corporation
5-(4-FLUOROBENZYL)-1,3-THIAZOL-2-AMINE 95.00%
5G
$ 1717.07

American Custom Chemicals Corporation
5-(4-FLUOROBENZYL)-1,3-THIAZOL-2-AMINE 95.00%
2.5G
$ 1337.31

American Custom Chemicals Corporation
5-(4-FLUOROBENZYL)-1,3-THIAZOL-2-AMINE 95.00%
1G
$ 910.76

Total 9 raw suppliers

Chemical Property of 5-(4-Fluoro-benzyl)-thiazol-2-ylamine

Chemical Property:

Vapor Pressure:3.39E-05mmHg at 25°C
Melting Point:135-136 °C(Solv: chloroform (67-66-3); carbon tetrachloride (56-23-5))
Boiling Point:354.2°C at 760 mmHg
PKA:5.07±0.10(Predicted)
Flash Point:168°C
PSA：67.15000
Density:1.317g/cm³
LogP:3.03640
XLogP3:2.7
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:208.04704763
Heavy Atom Count:14
Complexity:183

Purity/Quality:

98%min ^*data from raw suppliers

5-[(4-fluorophenyl)methyl]-1,3-thiazol-2-amine ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi
Hazard Codes:Xi

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=CC=C1CC2=CN=C(S2)N)F

Technology Process of 5-(4-Fluoro-benzyl)-thiazol-2-ylamine

There total 5 articles about 5-(4-Fluoro-benzyl)-thiazol-2-ylamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

: 17356-08-0
thiourea

: 807667-29-4
2-chloro-3-(4-fluorophenyl)propanal

: 315241-39-5
2-amino-5-(4-fluorobenzyl)-1,3-thiazole

Guidance literature:: In ethanol; Heating;
DOI:10.1023/B:RUJO.0000034976.75646.85

Reference yield: 77.0%

: tert-butyl-{5-[hydroxy-(4-fluorophenyl)methyl]thiazol-2-yl}carbamate

: 315241-39-5
2-amino-5-(4-fluorobenzyl)-1,3-thiazole

Guidance literature:: With triethylsilane; trifluoroacetic acid; In dichloromethane; at 20 ℃; Inert atmosphere;
DOI:10.1016/j.bmc.2014.12.006

Reference yield:

: 20893-71-4
4-fluorophenyldiazonium chloride

: 315241-39-5
2-amino-5-(4-fluorobenzyl)-1,3-thiazole

Guidance literature:: Multi-step reaction with 2 steps

1: 42 percent / CuCl₂*2H₂O / benzene; H₂O

2: 85 percent / ethanol / Heating

With CuCl₂*2H₂O; In ethanol; water; benzene; 1: Meerwein reaction;
DOI:10.1023/B:RUJO.0000034976.75646.85