807667-29-4Relevant articles and documents
Synthesis and anticancer properties of n-(5-r-benzyl-1,3-thiazol-2-yl)-2,5-dimethyl-3-furamides
Chaban, T. I.,Matiichuk, Y. E.,Matiychuk, V. S.,Ogurtsov, V. V.,Ostapiuk, Y. V.
, p. 75 - 84 (2020/06/01)
Aim. Study of the synthesis and anticancer activity of a series of N-(5-R-benzyl-1,3-thiazol-2-yl)-2,5-dimethyl-3-furamides. Methods. Organic synthesis, analytical and spectral methods, pharmacological screening. Results. N-(5-R-benzyl-1,3-thiazol-2-yl)-2
Synthesis and antitumor activities of new n-(5-benzylthiazol-2-yl)-2-(heteryl-5-ylsulfanyl)-acetamides
Ostapiuk, Yu. V.,Frolov,Vasylyschyn, R. Ya.,Matiychuk
, p. 59 - 71 (2018/05/15)
Aim. Synthesis of a series of new N-(5-benzyl-thiazol-2-yl)-2-(heteryl-5-ylsulfanyl)-acetamides and study of their anticancer activity. Methods. Organic synthesis, analytical and spectral methods, pharmacological screening. Results. [2-chloro-N-(5-aryl-1,
Discovery and potency optimization of 2-amino-5-arylmethyl-1,3-thiazole derivatives as potential therapeutic agents for prostate cancer
Krasavin, Mikhail,Karapetian, Ruben,Konstantinov, Igor,Gezentsvey, Yuri,Bukhryakov, Konstantin,Godovykh, Elena,Soldatkina, Olga,Lavrovsky, Yan,Sosnov, Andrei V.,Gakh, Andrei A.
experimental part, p. 420 - 427 (2009/11/30)
A new chemical series was identified via high-throughput screening as having antiproliferative activity on DU-145 human prostate carcinoma cell line (hit compound potency - 2.9 μM). Medicinal chemistry optimization of two peripheral diversity vectors of t
