Isothiazolo[3,4-b]pyridin-3-amine

Base Information

Chemical Name:Isothiazolo[3,4-b]pyridin-3-amine
CAS No.:42242-06-8
Molecular Formula:C6H5N3S
Molecular Weight:151.192
Hs Code.:
NSC Number:167881
UNII:W562JHP4TV
DSSTox Substance ID:DTXSID40195080
Wikidata:Q83067944
Mol file:42242-06-8.mol

Synonyms:42242-06-8;Isothiazolo[3,4-b]pyridin-3-amine;3-Aminoisothiazolo[3,4-b]pyridine;[1,2]thiazolo[3,4-b]pyridin-3-amine;Isothiazolo[3,4-b]pyridin-3-ylamine;Isothiazolo(3,4-b)pyridin-3-amine;NSC167881;W562JHP4TV;NSC 167881;NSC-167881;UNII-W562JHP4TV;SCHEMBL4067274;DTXSID40195080;MFCD08706345;AKOS006290032;isothiazolo[3,4-b]pyridin-3-yl-amine;SB37134;BS-37776;CS-0308077;EN300-106966;Z1198182071

Suppliers and Price of Isothiazolo[3,4-b]pyridin-3-amine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

J&W Pharmlab
Isothiazolo[3,4-b]pyridin-3-ylamine 97%
5g
$ 3998.00

J&W Pharmlab
Isothiazolo[3,4-b]pyridin-3-ylamine 97%
1g
$ 998.00

Crysdot
Isothiazolo[3,4-b]pyridin-3-amine 95+%
1g
$ 880.00

ChemBridge Corporation
isothiazolo[3,4-b]pyridin-3-amine 95%
200 μmol
$ 63.00

Alichem
Isothiazolo[3,4-b]pyridin-3-amine
1g
$ 771.12

AK Scientific
3-Aminoisothiazolo[3,4-b]pyridine
5g
$ 2524.00

AK Scientific
3-Aminoisothiazolo[3,4-b]pyridine
500mg
$ 749.00

Total 8 raw suppliers

Chemical Property of Isothiazolo[3,4-b]pyridin-3-amine

Chemical Property:

Vapor Pressure:0.000113mmHg at 25°C
Boiling Point:336.4°C at 760 mmHg
Flash Point:157.2°C
PSA：80.04000
Density:1.485g/cm³
LogP:1.85470
XLogP3:1.2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:0
Exact Mass:151.02041835
Heavy Atom Count:10
Complexity:130

Purity/Quality:

97% ^*data from raw suppliers

Isothiazolo[3,4-b]pyridin-3-ylamine 97% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC2=C(SN=C2N=C1)N

Technology Process of Isothiazolo[3,4-b]pyridin-3-amine

There total 2 articles about Isothiazolo[3,4-b]pyridin-3-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 24517-64-4
2-amino-3-pyridinecarbonitrile

: 42242-06-8
isothiazolo[3,4-b]pyridin-3-amine

Guidance literature:: 2-amino-3-pyridinecarbonitrile; With pyridine; hydrogen sulfide; triethylamine; at 20 ℃; for 20h; Sealed tube;

With dihydrogen peroxide; In methanol; water; at 20 ℃; for 5h;

Reference yield:

: 42242-05-7
2-aminopyridine-3-carbothioamide

: 42242-06-8
isothiazolo[3,4-b]pyridin-3-amine

Guidance literature:: With pyridine; dihydrogen peroxide;
DOI:10.1139/v73-262

Reference yield: 34.2%

: 2713-31-7
2,5-difluorophenol

: 42242-06-8
isothiazolo[3,4-b]pyridin-3-amine

: C₁₂H₆F₂N₄OS

Guidance literature:: 2,5-difluorophenol; isothiazolo[3,4-b]pyridin-3-amine; With sodium nitrite; In phosphoric acid; acetic acid; at 0 - 5 ℃; for 2h;

With water; In phosphoric acid; acetic acid; for 1h;