2-aminopyridine-3-carbothioamide

Base Information

• Chemical Name: 2-aminopyridine-3-carbothioamide
• CAS No.: 42242-05-7
• Molecular Formula: C6H7N3S
• Molecular Weight: 153.20488
• Hs Code.: 2933399090
• Mol file: 42242-05-7.mol

Synonyms:2-aminopyridine-3-carbothioamide

Chemical Property of 2-aminopyridine-3-carbothioamide

Chemical Property:

• Boiling Point: 343.8±52.0 °C(Predicted)
• PKA: 11.88±0.29(Predicted)
• PSA: 101.56000
• Density: 1.373±0.06 g/cm3(Predicted)
• LogP: 1.59990
• Storage Temp.: 2-8°C

Purity/Quality:

97% ^*data from raw suppliers

2-Aminopyridine-3-carbothioamide ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-aminopyridine-3-carbothioamide

There total 3 articles about 2-aminopyridine-3-carbothioamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

2-amino-3-pyridinecarbonitrile (24517-64-4) → 2-aminopyridine-3-carbothioamide (42242-05-7)

Guidance literature:

With sodium hydrogen sulfide monohydrate; magnesium chloride; In N,N-dimethyl-formamide; at 20 ℃; for 72h; Sealed tube;

DOI:10.1039/c4ob02207f

Reference yield:

2-aminopyridine-3-carboxamide (13438-65-8) → 2-aminopyridine-3-carbothioamide (42242-05-7)

Guidance literature:

With N,N,N,N,N,N-hexamethylphosphoric triamide; Hexamethyldisiloxane; phosphorous (V) sulfide; at 110 ℃; for 18h;

Reference yield:

→ 2-aminopyridine-3-carbothioamide (42242-05-7)

Guidance literature:

9, NH3, H2S;

DOI:10.1139/v73-262

upstream raw materials:

2-aminopyridine-3-carboxamide

2-amino-3-pyridinecarbonitrile

Downstream raw materials:

3-bromoisothiazolo[3,4-b]pyridine

isothiazolo[3,4-b]pyridin-3-amine