(3aR)-7α-Bromo-1,3,3aβ,4aα,5,6,7,8,8aβ,9-decahydro-4a,8,8-trimethylfuro[3,4-b][1]benzoxepin

Base Information

Chemical Name:(3aR)-7α-Bromo-1,3,3aβ,4aα,5,6,7,8,8aβ,9-decahydro-4a,8,8-trimethylfuro[3,4-b][1]benzoxepin
CAS No.:77249-86-6
Molecular Formula:C15H23BrO2
Molecular Weight:315.25
Hs Code.:
Mol file:77249-86-6.mol

Synonyms:(3aR,4aS,7S,8aS)-7-Bromo-1,3,3a,4a,5,6,7,8,8a,9-decahydro-4a,8,8-trimethylfuro[3,4-b][1]benzoxepin;(+)-palisadin A;Furo(3,4-b)(1)benzoxepin,7-bromo-1,3,3a,4a,5,6,7,8,8a,9-decahydro-4a,8,8-trimethyl-,(3aR,4aS,7S,8aS);

Suppliers and Price of (3aR)-7α-Bromo-1,3,3aβ,4aα,5,6,7,8,8aβ,9-decahydro-4a,8,8-trimethylfuro[3,4-b][1]benzoxepin

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 2 raw suppliers

Chemical Property of (3aR)-7α-Bromo-1,3,3aβ,4aα,5,6,7,8,8aβ,9-decahydro-4a,8,8-trimethylfuro[3,4-b][1]benzoxepin

Chemical Property:

Vapor Pressure:2.61E-05mmHg at 25°C
Boiling Point:368.9°C at 760 mmHg
Flash Point:147.8°C
PSA：18.46000
Density:1.3g/cm³
LogP:3.69030

Purity/Quality:: 95% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of (3aR)-7α-Bromo-1,3,3aβ,4aα,5,6,7,8,8aβ,9-decahydro-4a,8,8-trimethylfuro[3,4-b][1]benzoxepin

There total 1 articles about (3aR)-7α-Bromo-1,3,3aβ,4aα,5,6,7,8,8aβ,9-decahydro-4a,8,8-trimethylfuro[3,4-b][1]benzoxepin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 5389-87-7
1-chloro-3,7-dimethylocta-2,6-diene

: 77249-86-6
(+)-palisadin A

Guidance literature:: Multi-step reaction with 8 steps

1: 1.) n-BuLi / 1.)THF; 2.)THF, room temperature

2: n-BuLi / tetrahydrofuran / -65 °C

3: n-BuLi / tetrahydrofuran / 1 h / -70 - -65 °C

4: p-TsOH_.H₂O / methanol / 4 h / Ambient temperature

5: pyridine

6: LiBr_.H₂O / dimethylformamide / 2.5 h / 80 - 90 °C

8: 50 percent aq. K₂CO₃ / methanol / 0.25 h / Ambient temperature

With n-butyllithium; potassium carbonate; toluene-4-sulfonic acid; lithium bromide; In tetrahydrofuran; pyridine; methanol; N,N-dimethyl-formamide;