Dibromobimane

Base Information

Chemical Name:Dibromobimane
CAS No.:68654-25-1
Molecular Formula:C10H10 Br2 N2 O2
Molecular Weight: 350.00
Hs Code.:29339900
European Community (EC) Number:636-186-0
NSC Number:608550
DSSTox Substance ID:DTXSID70218736
Nikkaji Number:J777.662D
Wikidata:Q27132207
Metabolomics Workbench ID:62448
ChEMBL ID:CHEMBL2158899
Mol file:68654-25-1.mol

Synonyms:dibromobimane

Suppliers and Price of Dibromobimane

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
DIBROMOBIMANE 95.00%
50MG
$ 704.55

American Custom Chemicals Corporation
DIBROMOBIMANE 95.00%
500MG
$ 1593.90

Biosynth Carbosynth
Dibromobimane
5 mg
$ 50.00

Biosynth Carbosynth
Dibromobimane
10 mg
$ 80.00

Biosynth Carbosynth
Dibromobimane
25 mg
$ 150.00

Biosynth Carbosynth
Dibromobimane
50 mg
$ 225.00

Biosynth Carbosynth
Dibromobimane
100 mg
$ 380.00

Frontier Specialty Chemicals
Dibromobimane 98%
100mg
$ 111.00

Frontier Specialty Chemicals
Dibromobimane 98%
25mg
$ 43.00

Medical Isotopes, Inc.
Dibromobimane
250 mg
$ 1880.00

Total 17 raw suppliers

Chemical Property of Dibromobimane

Chemical Property:

Vapor Pressure:1.01E-05mmHg at 25°C
Melting Point:170-172oC(lit.)
Boiling Point:371.8°Cat760mmHg
PKA:-4.55±0.70(Predicted)
Flash Point:178.6°C
PSA：42.96000
Density:1.98g/cm³
LogP:1.60360
Storage Temp.:2-8°C
Solubility.:DMF: soluble
XLogP3:1.6
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:349.90885
Heavy Atom Count:16
Complexity:414

Purity/Quality:

99% ^*data from raw suppliers

DIBROMOBIMANE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi
Hazard Codes:Xi
Statements: 36/37/38
Safety Statements: 26-36

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

Canonical SMILES:CC1=C(N2C(=C(C(=O)N2C1=O)C)CBr)CBr
Uses A cross linking reagent for proteins, thiols in myosin, hemoglobin and mitochondrial ATPase multiple labeled product that can be fixed with aldehydes A cross linking reagent for proteins, thiols in myosin, hemoglobin and mitochondrial ATPase. Dibromobimane, a bifunctional thiol reagent, is used as a cross-linking agent for cysteine mapping and studies on protein structure/conformation and cross-linking processes.

Technology Process of Dibromobimane

There total 6 articles about Dibromobimane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 76.0%

: 68654-22-8
9,10-dioxa-syn-(methyl,methyl)bimane

: 68654-25-1
syn-4,6-bis(bromomethyl)-3,7-dimethyl-1,5-diazabicyclo<3.3.0>octa-3,6-diene-2,8-dione

Guidance literature:: With bromine; In dichloromethane; for 0.5h; Product distribution; Ambient temperature; other reaction time; chemical properties of 9,10-dioxabimanes: electrophylic reactions, reduction and oxidation, reactions with bases, thermal reactions;
DOI:10.1021/ja00535a028

Reference yield: 2.2%

: 68654-22-8
9,10-dioxa-syn-(methyl,methyl)bimane

: 71418-44-5
monobromobimane

: 68654-25-1
syn-4,6-bis(bromomethyl)-3,7-dimethyl-1,5-diazabicyclo<3.3.0>octa-3,6-diene-2,8-dione

Guidance literature:: With bromine; In dichloromethane; Ambient temperature;
DOI:10.1021/ja00535a028

Reference yield:

: 609-14-3
2-acetylpropanoic acid ethyl ester

: 68654-25-1
syn-4,6-bis(bromomethyl)-3,7-dimethyl-1,5-diazabicyclo<3.3.0>octa-3,6-diene-2,8-dione

Guidance literature:: Multi-step reaction with 4 steps

1: NH₂NH₂ / ethanol / 1 h / Heating

2: 73.1 percent / Cl₂ / 1,2-dichloro-ethane / Heating

3: 12.5 percent / hydrated potassium carbonate / CH₂Cl₂ / 12 h / Ambient temperature

4: 2.2 percent / Br₂ / CH₂Cl₂ / Ambient temperature

With bromine; chlorine; potassium carbonate; hydrazine; In ethanol; dichloromethane; 1,2-dichloro-ethane;
DOI:10.1021/ja00535a028