4-Chloro-1-methyl-1H-pyrrolo[3,2-c]pyridine-3-carbaldehyde

Base Information

Chemical Name:4-Chloro-1-methyl-1H-pyrrolo[3,2-c]pyridine-3-carbaldehyde
CAS No.:97989-41-8
Molecular Formula:C9H7ClN2O
Molecular Weight:194.61800
Hs Code.:2933990090
DSSTox Substance ID:DTXSID90541119
Wikidata:Q82417363
Mol file:97989-41-8.mol

Synonyms:4-Chloro-1-methyl-1H-pyrrolo[3,2-c]pyridine-3-carbaldehyde;97989-41-8;4-CHLORO-1-METHYLPYRROLO[3,2-C]PYRIDINE-3-CARBALDEHYDE;1H-Pyrrolo[3,2-c]pyridine-3-carboxaldehyde, 4-chloro-1-methyl-;4-Chloro-1-methyl-1H-pyrrolo[3,2-c]pyridine-3-carboxaldehyde;DTXSID90541119;4-Chloro-1-methyl-1H-pyrrolo[3,2-c]pyridine-3-carbaldehyde ,97%;AKOS006288926;A904746;J-514894

Suppliers and Price of 4-Chloro-1-methyl-1H-pyrrolo[3,2-c]pyridine-3-carbaldehyde

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
4-Chloro-1-methyl-1H-pyrrolo[3,2-c]pyridine-3-carbaldehyde 95+%
1g
$ 442.00

Chemenu
4-Chloro-1-methyl-1H-pyrrolo[3,2-c]pyridine-3-carbaldehyde 95%
1g
$ 417.00

American Custom Chemicals Corporation
4-CHLORO-1-METHYL-1H-PYRROLO(3,2-C)PYRIDINE-3-CARBALDEHYDE 95.00%
5MG
$ 504.42

Alichem
4-Chloro-1-methyl-1H-pyrrolo[3,2-c]pyridine-3-carbaldehyde
1g
$ 388.80

Total 11 raw suppliers

Chemical Property of 4-Chloro-1-methyl-1H-pyrrolo[3,2-c]pyridine-3-carbaldehyde

Chemical Property:

Vapor Pressure:0mmHg at 25°C
Melting Point:210-211 °C(Solv: ethanol (64-17-5))
Boiling Point:388.9±37.0 °C(Predicted)
PKA:3.67±0.50(Predicted)
PSA：34.89000
Density:1.37±0.1 g/cm3(Predicted)
LogP:2.03920
Storage Temp.:2-8°C
XLogP3:1.4
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:194.0246905
Heavy Atom Count:13
Complexity:212

Purity/Quality:

97% ^*data from raw suppliers

4-Chloro-1-methyl-1H-pyrrolo[3,2-c]pyridine-3-carbaldehyde 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CN1C=C(C2=C1C=CN=C2Cl)C=O

Technology Process of 4-Chloro-1-methyl-1H-pyrrolo[3,2-c]pyridine-3-carbaldehyde

There total 3 articles about 4-Chloro-1-methyl-1H-pyrrolo[3,2-c]pyridine-3-carbaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

: 68-12-2,33513-42-7
N,N-dimethyl-formamide

: 27382-01-0
1-methyl-4-chloro-1H-pyrrolo<3,2-c>pyridine

: 97989-41-8
4-chloro-3-formyl-1-methylpyrrolo<3,2-c>pyridine

Guidance literature:: With trichlorophosphate; at 100 ℃; for 2h; 0-10 deg C (adding);
DOI:10.1016/S0040-4020(01)96558-5

Reference yield: 43.0%

: 100-97-0
hexamethylenetetramine

: 27382-01-0
1-methyl-4-chloro-1H-pyrrolo<3,2-c>pyridine

: 97989-41-8
4-chloro-3-formyl-1-methylpyrrolo<3,2-c>pyridine

Guidance literature:: With acetic acid; at 100 ℃; for 1h;
DOI:10.1021/acs.jmedchem.1c00720

Reference yield:

: 60290-21-3
4-chloro-1H-pyrrolo-[3,2-c]-pyridine

: 97989-41-8
4-chloro-3-formyl-1-methylpyrrolo<3,2-c>pyridine

Guidance literature:: Multi-step reaction with 2 steps

1: sodium hydride / N,N-dimethyl-formamide; mineral oil / 1 h / 0 - 20 °C

2: acetic acid / 1 h / 100 °C

With sodium hydride; acetic acid; In N,N-dimethyl-formamide; mineral oil;
DOI:10.1021/acs.jmedchem.1c00720