1-(3-Chlorophenyl)cyclopropaneMethanol

Base Information

• Chemical Name: 1-(3-Chlorophenyl)cyclopropaneMethanol
• CAS No.: 98480-33-2
• Molecular Formula: C₁₀H₁₁ClO
• Molecular Weight: 182.65
• Mol file: 98480-33-2.mol

Synonyms:CYCLOPROPANEMETHANOL,1-(3-CHLOROPHENYL);1-(3-Chlorophenyl)cyclopropanemethanol;1-(M-CHLOROPHENYL)CYCLOPROPANEMETHANOL;[1-(3-CHLORO-PHENYL)-CYCLOPROPYL]-METHANOL;

Chemical Property of 1-(3-Chlorophenyl)cyclopropaneMethanol

Chemical Property:

• PSA: 20.23000
• LogP: 2.36390

Purity/Quality:

98%min ^*data from raw suppliers

[1-(3-CHLORO-PHENYL)-CYCLOPROPYL]-METHANOL 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1-(3-Chlorophenyl)cyclopropaneMethanol

There total 1 articles about 1-(3-Chlorophenyl)cyclopropaneMethanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1-(3-chloro-phenyl)cyclopropanecarbonitrile (124276-32-0) → (1-(3-chlorophenyl)cyclopropyl)methanol (98480-33-2)

Guidance literature:

Multi-step reaction with 2 steps

1: lithium hydroxide / water / 100 °C

2: lithium aluminium tetrahydride / tetrahydrofuran / 2 h / 0 - 20 °C

With lithium aluminium tetrahydride; lithium hydroxide; In tetrahydrofuran; water;

DOI:10.1002/anie.201603153

Reference yield:

(1-(3-chlorophenyl)cyclopropyl)methanol (98480-33-2) → C14H19ClOSi + C14H19ClOSi

Guidance literature:

Multi-step reaction with 2 steps

1: tris(triphenylphosphine)ruthenium(II) chloride / benzene / 12 h / 50 °C / Inert atmosphere; Glovebox

2: chloro(1,5-cyclooctadiene)rhodium(I) dimer; (S)-DTBM-SEGPHOS / tetrahydrofuran; cyclohexene / 24 h / 50 °C / Inert atmosphere; Glovebox

With chloro(1,5-cyclooctadiene)rhodium(I) dimer; tris(triphenylphosphine)ruthenium(II) chloride; (S)-DTBM-SEGPHOS; In tetrahydrofuran; cyclohexene; benzene;

DOI:10.1002/anie.201603153

upstream raw materials:

1-(3-chloro-phenyl)cyclopropanecarbonitrile

Refernces