124276-32-0

Basic information

• Product Name: 1-(3-CHLORO-PHENYL)-CYCLOPROPANECARBONITRILE
• Synonyms: 1-(3-CHLORO-PHENYL)-CYCLOPROPANECARBONITRILE;1-(3-CHLOROPHENYL)CYCLOPROPANE-1-CARBONITRILE;1-(3-Chlorophenyl)-1-cyanocyclopropane
• CAS NO: 124276-32-0
• Molecular Formula: C₁₀H₈ClN
• Molecular Weight: 177.63022
• Mol File: 124276-32-0.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 316.5 °C at 760 mmHg
• Flash Point: 142.6 °C
• Appearance: /
• Density: 1.24 g/cm³
• Vapor Pressure: 0.000409mmHg at 25°C
• Refractive Index: 1.589
• Storage Temp.: Room temperature.
• CAS DataBase Reference: 1-(3-CHLORO-PHENYL)-CYCLOPROPANECARBONITRILE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(3-CHLORO-PHENYL)-CYCLOPROPANECARBONITRILE(124276-32-0)
• EPA Substance Registry System: 1-(3-CHLORO-PHENYL)-CYCLOPROPANECARBONITRILE(124276-32-0)

Safety Data

• Hazard Codes: Xi
• Statements: 41
• Safety Statements: 26-39
• Hazardous Substances Data: 124276-32-0(Hazardous Substances Data)

Usage

Uses

1-(3-Chlorophenyl)cyclopropanecarbonitrile

InChI:InChI=1/C10H8ClN/c11-9-3-1-2-8(6-9)10(7-12)4-5-10/h1-3,6H,4-5H2

Upstream product

• 1529-41-5 3-chloro-benzeneacetonitrile 
• 106-93-4 ethylene dibromide 
• 96-49-1 [1,3]-dioxolan-2-one 
• 107-04-0 1-Bromo-2-chloroethane 

Downstream Products

• 124276-34-2 1-(3-chlorophenyl)cyclopropane-1-carboxylic acid 
• 98480-33-2 (1-(3-chlorophenyl)cyclopropyl)methanol 
• 115816-31-4 C₁₀H₁₂ClN 

Relevant articles and documents

Efficient cyclopropanation of active methylene compounds. A serendipitous discovery

Cyclopropanation of active methylene compounds has been achieved in good yields with ethylene carbonate as the cyclopropanating agent in the presence of a simple base.

Lewis Basic Sulfide Catalyzed Electrophilic Bromocyclization of Cyclopropylmethyl Amide

A Lewis basic sulfide catalyzed electrophilic bromocyclization of cyclopropylmethyl amide has been developed. The catalytic protocol is applicable to both 1,1- and 1,2-substituted cyclopropylmethyl amides, giving oxazolines and oxazines in good yields and excellent diastereoselectivity.

Methods and Compositions for Selectin Inhibition

The present teachings relate to novel compounds of formula I: wherein the constituent variables are as defined herein. Compounds of the present teachings can act as antagonists of the mammalian adhesion proteins known as selecting. Methods for treating or preventing selectin-mediated disorders are provided, which include administration of these compounds in a therapeutically effective amount.