1,2-Cyclobutanedimethanol, diacetate, cis-

Base Information

Chemical Name:1,2-Cyclobutanedimethanol, diacetate, cis-
CAS No.:98515-98-1
Molecular Formula:C10H16O4
Molecular Weight:200.235
Hs Code.:

Synonyms:

Suppliers and Price of 1,2-Cyclobutanedimethanol, diacetate, cis-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 6 raw suppliers

Chemical Property of 1,2-Cyclobutanedimethanol, diacetate, cis-

Chemical Property:

Purity/Quality:: 99%, ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

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Technology Process of 1,2-Cyclobutanedimethanol, diacetate, cis-

There total 2 articles about 1,2-Cyclobutanedimethanol, diacetate, cis- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 4462-96-8
cis-1,2-cyclobutane dicarboxylic anhydride

: 98515-98-1
(1R,2S)-cyclobutane-1,2-diylbis(methylene) diacetate

Guidance literature:: Multi-step reaction with 2 steps

1: LiAlH₄; diethyl ether

2: acetic acid

With lithium aluminium tetrahydride; diethyl ether; acetic acid;
DOI:10.1021/ja01615a034

Reference yield:

: 4462-96-8
cis-1,2-cyclobutane dicarboxylic anhydride

: 108-24-7
acetic anhydride

: 98515-98-1
(1R,2S)-cyclobutane-1,2-diylbis(methylene) diacetate

Guidance literature:: at 50 ℃;

Reference yield:

: 98515-98-1
(1R,2S)-cyclobutane-1,2-diylbis(methylene) diacetate

: 1883727-34-1
(1S,3’R,6’R,7’S,9’E,11’S,12’R)-6-chloro-7'-methoxy-11’,12’-dimethyl-3,4-dihydro-2H,15’H-spiro[naphthalene-1,22’-[20]oxa[13]thia[1,14]diazatetracyclo[14.7.2.03,6.019,24]pentacosa[9,16,18,24]tetraen]-15’-one-13’,13'-dioxide

Guidance literature:: Multi-step reaction with 10 steps

1.1: sodium citrate / water / 0.2 °C / pH Ca₅₄₅ / Enzymatic reaction

2.1: 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; [bis(acetoxy)iodo]benzene / dichloromethane / 15 - 20 °C

2.2: 48 h / 1.8 - 20 °C

3.1: dichloromethane; acetic acid / 0.17 h / 20 °C

3.2: 1.17 h / 0 °C

4.1: potassium hydroxide / methanol / 4 h / 20 °C

4.2: pH 7

5.1: dimethyl sulfoxide; oxalyl dichloride; triethylamine / dichloromethane / 2.5 h / -70 °C / Inert atmosphere

6.1: (1R,2S)-2-(morpholin-4-yl)-1-phenyl-1-propanol; n-butyllithium / toluene; hexane / 1 h / 0 - 12 °C

6.2: 0 h / -10 - -5 °C

7.1: water; lithium hydroxide monohydrate / tetrahydrofuran; methanol / 4 h / 50 °C

7.2: 0 °C / pH 3

8.1: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; dmap / dichloromethane / 0 - 20 °C

9.1: Hoveyda-Grubbs catalyst second generation / dichloromethane / 15 h / 45 °C / Inert atmosphere

10.1: potassium hexamethylsilazane / tetrahydrofuran; 2-methyltetrahydrofuran / 2 h / -44 - 20 °C / Inert atmosphere

With dmap; (1R,2S)-2-(morpholin-4-yl)-1-phenyl-1-propanol; n-butyllithium; Hoveyda-Grubbs catalyst second generation; oxalyl dichloride; 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; lithium hydroxide monohydrate; [bis(acetoxy)iodo]benzene; water; sodium citrate; potassium hexamethylsilazane; dimethyl sulfoxide; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine; potassium hydroxide; In tetrahydrofuran; 2-methyltetrahydrofuran; methanol; hexane; dichloromethane; water; acetic acid; toluene;