1H-Azepine-1,4-dicarboxylic acid, hexahydro-3-oxo-, 1-(1,1-dimethylethyl) 4-ethyl ester

Base Information

Chemical Name:1H-Azepine-1,4-dicarboxylic acid, hexahydro-3-oxo-, 1-(1,1-dimethylethyl) 4-ethyl ester
CAS No.:98977-38-9
Molecular Formula:C₁₄H₂₃NO₅
Molecular Weight:285.34
Hs Code.:

Synonyms:

Suppliers and Price of 1H-Azepine-1,4-dicarboxylic acid, hexahydro-3-oxo-, 1-(1,1-dimethylethyl) 4-ethyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
1-tert-Butyl4-ethyl3-oxoazepane-1,4-dicarboxylate 95+%
1g
$ 895.00

Chemenu
1-tert-Butyl4-ethyl3-oxoazepane-1,4-dicarboxylate 95%
1g
$ 771.00

Alichem
1-Tert-butyl4-ethyl3-oxoazepane-1,4-dicarboxylate
250mg
$ 399.64

Alichem
1-Tert-butyl4-ethyl3-oxoazepane-1,4-dicarboxylate
1g
$ 960.30

AK Scientific
1-Tert-butyl4-ethyl3-oxoazepane-1,4-dicarboxylate
5g
$ 2327.00

AK Scientific
1-Tert-butyl4-ethyl3-oxoazepane-1,4-dicarboxylate
250mg
$ 783.00

Total 7 raw suppliers

Chemical Property of 1H-Azepine-1,4-dicarboxylic acid, hexahydro-3-oxo-, 1-(1,1-dimethylethyl) 4-ethyl ester

Chemical Property:

PSA：72.91000
LogP:1.70360

Purity/Quality:

97% ^*data from raw suppliers

1-tert-Butyl4-ethyl3-oxoazepane-1,4-dicarboxylate 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 1H-Azepine-1,4-dicarboxylic acid, hexahydro-3-oxo-, 1-(1,1-dimethylethyl) 4-ethyl ester

There total 8 articles about 1H-Azepine-1,4-dicarboxylic acid, hexahydro-3-oxo-, 1-(1,1-dimethylethyl) 4-ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 48.0%

: 623-73-4
diazoacetic acid ethyl ester

: 98977-36-7
3-oxo-piperidine-1-carboxylic acid tert-butyl ester

: 98977-37-8
ethyl (+/-)-1-(tert-butyloxycarbonyl)-4-oxoperhydroazepine-3-carboxylate

: 98977-38-9
ethyl (+/-)-1-(tert-butyloxycarbonyl)-3-oxoperhydroazepine-4-carboxylate

Guidance literature:: 3-oxo-piperidine-1-carboxylic acid tert-butyl ester; With boron trifluoride diethyl etherate; In diethyl ether; at -30 ℃; for 0.166667h;

diazoacetic acid ethyl ester; at -30 ℃; for 1h;
DOI:10.1016/j.tetlet.2018.11.047

Reference yield: 11.0%

: 623-73-4
diazoacetic acid ethyl ester

: 98977-36-7
3-oxo-piperidine-1-carboxylic acid tert-butyl ester

: 98977-38-9
ethyl (+/-)-1-(tert-butyloxycarbonyl)-3-oxoperhydroazepine-4-carboxylate

Guidance literature:: With boron trifluoride diethyl etherate; In di-isopropyl ether; at 0 ℃; for 1.5h;

Reference yield:

: C₁₆H₂₉NO₆

: C₁₄H₂₃NO₅

: 98977-38-9
ethyl (+/-)-1-(tert-butyloxycarbonyl)-3-oxoperhydroazepine-4-carboxylate

Guidance literature:: With sodium tert-pentoxide; In toluene; for 16h; Reagent/catalyst; Overall yield = 81.18 %; Overall yield = 10.56 g; Reflux;