Pyridine, 1,2,3,6-tetrahydro-4-(3-methoxyphenyl)-1-(phenylmethyl)-

Base Information

Chemical Name:Pyridine, 1,2,3,6-tetrahydro-4-(3-methoxyphenyl)-1-(phenylmethyl)-
CAS No.:99329-65-4
Molecular Formula:C19H21NO
Molecular Weight:279.382
Hs Code.:
DSSTox Substance ID:DTXSID20444487
Nikkaji Number:J1.402.287B
Wikidata:Q82262632

Synonyms:99329-65-4;Pyridine, 1,2,3,6-tetrahydro-4-(3-methoxyphenyl)-1-(phenylmethyl)-;1-Benzyl-4-(3-methoxyphenyl)-1,2,3,6-tetrahydropyridine;1-benzyl-4-(3-methoxyphenyl)-3,6-dihydro-2H-pyridine;SCHEMBL4827185;DTXSID20444487;FT-0702974

Suppliers and Price of Pyridine, 1,2,3,6-tetrahydro-4-(3-methoxyphenyl)-1-(phenylmethyl)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of Pyridine, 1,2,3,6-tetrahydro-4-(3-methoxyphenyl)-1-(phenylmethyl)-

Chemical Property:

XLogP3:3.6
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:4
Exact Mass:279.162314293
Heavy Atom Count:21
Complexity:346

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=CC=CC(=C1)C2=CCN(CC2)CC3=CC=CC=C3

Technology Process of Pyridine, 1,2,3,6-tetrahydro-4-(3-methoxyphenyl)-1-(phenylmethyl)-

There total 7 articles about Pyridine, 1,2,3,6-tetrahydro-4-(3-methoxyphenyl)-1-(phenylmethyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

: 3612-20-2
1-phenylmethyl-4-piperidone

: 36282-40-3
(3-methoxyphenyl)magnesium bromide

: 99329-65-4
1-benzyl-4-(3-methoxy-phenyl)-1,2,3,6-tetrahydro-pyridine

Guidance literature:: 1-phenylmethyl-4-piperidone; (3-methoxyphenyl)magnesium bromide;

With 4-tosylphenol; at 120 ℃;

Reference yield: 58.0%

: 99329-68-7
1-Benzyl-4-(3-methoxy-phenyl)-piperidin-4-ol

: 99329-65-4
1-benzyl-4-(3-methoxy-phenyl)-1,2,3,6-tetrahydro-pyridine

Guidance literature:: With toluene-4-sulfonic acid; In toluene; for 6h; Heating;
DOI:10.1021/jm00160a039

Reference yield:

: 3612-20-2
1-phenylmethyl-4-piperidone

: 99329-65-4
1-benzyl-4-(3-methoxy-phenyl)-1,2,3,6-tetrahydro-pyridine

Guidance literature:: Multi-step reaction with 2 steps

1.1: n-BuLi / tetrahydrofuran / 2 h / -60 °C

1.2: tetrahydrofuran / 2 h / 20 °C

2.1: 51.4 g / p-toluenesulfonic acid monohydrate / toluene / 6 h / Heating

With n-butyllithium; toluene-4-sulfonic acid; In tetrahydrofuran; toluene;
DOI:10.1039/b618875c