2-(6-(4-(4-benzylphthalazin-1-yl)piperazin-1-yl)pyridin-3-yl)propan-2-ol

Base Information

Chemical Name:2-(6-(4-(4-benzylphthalazin-1-yl)piperazin-1-yl)pyridin-3-yl)propan-2-ol
CAS No.:1057677-92-5
Molecular Formula:C27H29N5O
Molecular Weight:439.56
Hs Code.:
Mol file:1057677-92-5.mol

Synonyms:2-(6-(4-(4-benzylphthalazin-1-yl)piperazin-1-yl)pyridin-3-yl)propan-2-ol

Suppliers and Price of 2-(6-(4-(4-benzylphthalazin-1-yl)piperazin-1-yl)pyridin-3-yl)propan-2-ol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
2-(6-(4-(4-BENZYLPHTHALAZIN-1-YL)PIPERAZIN-1-YL)PYRIDIN-3-YL)PROPAN-2-OL 95.00%
5MG
$ 504.31

Total 2 raw suppliers

Chemical Property of 2-(6-(4-(4-benzylphthalazin-1-yl)piperazin-1-yl)pyridin-3-yl)propan-2-ol

Chemical Property:

PSA：65.38000
LogP:4.29960

Purity/Quality:

99% ^*data from raw suppliers

2-(6-(4-(4-BENZYLPHTHALAZIN-1-YL)PIPERAZIN-1-YL)PYRIDIN-3-YL)PROPAN-2-OL 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 2-(6-(4-(4-benzylphthalazin-1-yl)piperazin-1-yl)pyridin-3-yl)propan-2-ol

There total 1 articles about 2-(6-(4-(4-benzylphthalazin-1-yl)piperazin-1-yl)pyridin-3-yl)propan-2-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 71.0%

: 917-64-6
methyl magnesium iodide

: 1057677-65-2
6-[4-(4-benzylphthalazin-1-yl)piperazin-1-yl]nicotinic acid ethyl ester

: 1057677-92-5
2-{6-[4-(4-benzylphthalazin-1-yl)piperazin-1-yl]pyridin-3-yl}propan-2-ol

Guidance literature:: methyl magnesium iodide; 6-[4-(4-benzylphthalazin-1-yl)piperazin-1-yl]nicotinic acid ethyl ester; In tetrahydrofuran; diethyl ether; at 23 ℃; for 2h; Inert atmosphere;

With water; ammonium chloride; In tetrahydrofuran; diethyl ether; Saturated solution;
DOI:10.1021/jm900309j

Reference yield: 60.0%

: 1057677-92-5
2-{6-[4-(4-benzylphthalazin-1-yl)piperazin-1-yl]pyridin-3-yl}propan-2-ol

: 1449714-74-2
C₂₇H₂₅N₅O

: 1449714-75-3
C₂₇H₂₇N₅O

Guidance literature:: With copper(l) iodide; oxygen; acetic acid; In dimethyl sulfoxide; at 110 ℃; for 16h;
DOI:10.1021/ja405471h

Reference yield: 39.0%

: 1057677-92-5
2-{6-[4-(4-benzylphthalazin-1-yl)piperazin-1-yl]pyridin-3-yl}propan-2-ol

: 75-05-8,26809-02-9
acetonitrile

: 1057678-76-8
N-(1-{6-[4-(4-benzyl-phthalazin-1-yl)-piperazin-1-yl]-pyridin-3-yl}-1-methyl-ethyl)-acetamide

Guidance literature:: 2-{6-[4-(4-benzylphthalazin-1-yl)piperazin-1-yl]pyridin-3-yl}propan-2-ol; acetonitrile; With sulfuric acid; acetic acid; at 0 - 20 ℃; for 3.16667h;

With sodium carbonate; In water; pH=~ 7;