4-(2-Chloropyridin-3-yl)pyrimidin-2-amine

Base Information

Chemical Name:4-(2-Chloropyridin-3-yl)pyrimidin-2-amine
CAS No.:870221-49-1
Molecular Formula:C9H7ClN4
Molecular Weight:206.634
Hs Code.:2933990090
European Community (EC) Number:804-621-5
DSSTox Substance ID:DTXSID70694258
Wikidata:Q82623297
Mol file:870221-49-1.mol

Synonyms:4-(2-chloropyridin-3-yl)pyrimidin-2-amine;870221-49-1;4-(2-Chloro-pyridin-3-yl)-pyrimidin-2-ylamine;SCHEMBL503736;DTXSID70694258;DKCVVHMYFZBDAK-UHFFFAOYSA-N;VJB22149;MFCD18157687;AKOS015851075;NE-0721;CS-0314498;FT-0682721;A862933;J-513295

Suppliers and Price of 4-(2-Chloropyridin-3-yl)pyrimidin-2-amine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Matrix Scientific
4-(2-Chloropyridin-3-yl)pyrimidin-2-amine >95%
500mg
$ 405.00

Matrix Scientific
4-(2-Chloropyridin-3-yl)pyrimidin-2-amine >95%
1g
$ 545.00

Crysdot
4-(2-Chloropyridin-3-yl)pyrimidin-2-amine 95+%
1g
$ 722.00

Chemenu
4-(2-Chloropyridin-3-yl)pyrimidin-2-amine 95%
1g
$ 682.00

Alfa Aesar
2-Amino-4-(2-chloro-3-pyridyl)pyrimidine, 97%
1g
$ 417.00

Alfa Aesar
2-Amino-4-(2-chloro-3-pyridyl)pyrimidine, 97%
250mg
$ 140.00

AK Scientific
4-(2-Chloropyridin-3-yl)pyrimidin-2-amine
500mg
$ 596.00

Total 13 raw suppliers

Chemical Property of 4-(2-Chloropyridin-3-yl)pyrimidin-2-amine

Chemical Property:

PSA：64.69000
LogP:2.35540
XLogP3:1.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:1
Exact Mass:206.0359239
Heavy Atom Count:14
Complexity:190

Purity/Quality:

97% ^*data from raw suppliers

4-(2-Chloropyridin-3-yl)pyrimidin-2-amine >95% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=C(N=C1)Cl)C2=NC(=NC=C2)N

Technology Process of 4-(2-Chloropyridin-3-yl)pyrimidin-2-amine

There total 3 articles about 4-(2-Chloropyridin-3-yl)pyrimidin-2-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

: 870221-50-4
(E)-1-(2-chloropyridin-3-yl)-3-(dimethylamino)-prop-2-en-1-one

: 870221-49-1
4-(2-chloropyridin-3-yl)pyrimidin-2-amine

Guidance literature:: With guanidine hydrochloride; sodium methylate; In methanol; at 50 ℃; Inert atmosphere;
DOI:10.1021/acs.jmedchem.5b00183

Reference yield:

: 870221-50-4
(E)-1-(2-chloropyridin-3-yl)-3-(dimethylamino)-prop-2-en-1-one

: 50-01-1
guanidine hydrochloride

: 870221-49-1
4-(2-chloropyridin-3-yl)pyrimidin-2-amine

Guidance literature:: guanidine hydrochloride; With sodium methylate; In methanol; at 20 ℃; for 0.5h;

(E)-1-(2-chloropyridin-3-yl)-3-(dimethylamino)-prop-2-en-1-one; In methanol; at 50 ℃; for 24h;

Reference yield:

: 870221-50-4
(E)-1-(2-chloropyridin-3-yl)-3-(dimethylamino)-prop-2-en-1-one

: guanidine hydrochloride salt

: 870221-49-1
4-(2-chloropyridin-3-yl)pyrimidin-2-amine

Guidance literature:: guanidine hydrochloride salt; With sodium; In methanol; at 20 ℃; for 0.5h; Inert atmosphere;

(E)-1-(2-chloropyridin-3-yl)-3-(dimethylamino)-prop-2-en-1-one; In methanol; at 50 ℃; for 24h;