Moxifloxacin isoMer

Base Information

Chemical Name:Moxifloxacin isoMer
CAS No.:268545-13-7
Molecular Formula:C21H24FN3O4
Molecular Weight:401.43
Hs Code.:
UNII:JU4MC5ZQ7G
Mol file:268545-13-7.mol

Synonyms:Moxifloxacin isoMer;268545-13-7;Dexmoxifloxacin;1346747-14-5;(+)-Moxifloxacin;Moxifloxacin, (R)-;JU4MC5ZQ7G;1-Cyclopropyl-6-fluoro-7-((4aR,7aR)-hexahydro-1H-pyrrolo[3,4-b]pyridin-6(2H)-yl)-8-methoxy-4-oxo-1,4-dihydroquinoline-3-carboxylic acid;3-Quinolinecarboxylic acid, 1-cyclopropyl-6-fluoro-1,4-dihydro-8-Methoxy-7-[(4aR,7aR)-octahydro-6H-p;7-[(4aR,7aR)-1,2,3,4,4a,5,7,7a-octahydropyrrolo[3,4-b]pyridin-6-yl]-1-cyclopropyl-6-fluoro-8-methoxy-4-oxoquinoline-3-carboxylic acid;1-Cyclopropyl-6-fluoro-7-(cis-hexahydro-1H-pyrrolo[3,4-b]pyridin-6(2H)-yl)-8-methoxy-4-oxo-1,4-dihydroquinoline-3-carboxylic acid;1-Cyclopropyl-6-fluoro-8-methoxy-7-((4aR,7aR)-octahydro-6H-pyrrolo(3,4-b)pyridin-6-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid;1-cyclopropyl-6-fluoro-8-methoxy-7-((4aR,7aR)-octahydro-6H-pyrrolo[3,4-b]pyridin-6-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid;3-Quinolinecarboxylic acid, 1-cyclopropyl-6-fluoro-1,4-dihydro-8-methoxy-7-((4aR,7aR)-octahydro-6H-pyrrolo(3,4-b)pyridin-6-yl)-4-oxo-;MFCD04117996;UNII-JU4MC5ZQ7G;SCHEMBL12156451;1-Cyclopropyl-6-fluoro-1,4-dihydro-8-methoxy-7-[(4aR,7aR)-octahydro-6H-pyrrolo[3,4-b]pyridin-6-yl]-4-oxo-3-quinolinecarboxylic acid;BCP10081;FD10563;Moxifloxacin hydrochloride impurity G [USP];CS-0164454;EN300-21645518;MOXIFLOXACIN HYDROCHLORIDE IMPURITY G [USP IMPURITY];1-Cyclopropyl-6-fluoro-8-methoxy-7-((4aR,7aR)-octahydro-6H-pyrrolo[3,4-b]pyridin-6-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic Acid (Moxifloxacin Impurity pound(c);7-[(4aR,7aR)-octahydro-1H-pyrrolo[3,4-b]pyridin-6-yl]-1-cyclopropyl-6-fluoro-8-methoxy-4-oxo-1,4-dihydroquinoline-3-carboxylic acid

Suppliers and Price of Moxifloxacin isoMer

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
1-Cyclopropyl-6-fluoro-7-((4aR,7aR)-hexahydro-1H-pyrrolo[3,4-b]pyridin-6(2H)-yl)-8-methoxy-4-oxo-1,4-dihydroquinoline-3-carboxylicacid 97%
25mg
$ 673.00

Total 34 raw suppliers

Chemical Property of Moxifloxacin isoMer

Chemical Property:

Melting Point:226-228°C (dec.)
Boiling Point:636.4±55.0 °C(Predicted)
PKA:6.43±0.50(Predicted)
PSA：83.80000
Density:1.408
LogP:2.76430
Storage Temp.:-20?C Freezer
Solubility.:DMSO (Slightly), Methanol (Slightly), Water (Slightly)
XLogP3:0.6
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:8
Rotatable Bond Count:4
Exact Mass:401.17508442
Heavy Atom Count:29
Complexity:727

Purity/Quality:

97% ^*data from raw suppliers

1-Cyclopropyl-6-fluoro-7-((4aR,7aR)-hexahydro-1H-pyrrolo[3,4-b]pyridin-6(2H)-yl)-8-methoxy-4-oxo-1,4-dihydroquinoline-3-carboxylicacid 97% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:COC1=C2C(=CC(=C1N3CC4CCCNC4C3)F)C(=O)C(=CN2C5CC5)C(=O)O
Isomeric SMILES:COC1=C2C(=CC(=C1N3C[C@H]4CCCN[C@H]4C3)F)C(=O)C(=CN2C5CC5)C(=O)O
Uses d-Moxifloxacin is used in the preparation and responsible for antimycobacterial and cytotoxic activity of propylene-triazole-methylene-tethered (thio)semicarbazone-isatin-moxifloxacin hybrids. The (R,R)-Isomer of Moxifloxacin

Technology Process of Moxifloxacin isoMer

There total 19 articles about Moxifloxacin isoMer which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

: 112811-72-0
1-cyclopropyl-6,7-difluoro-1,4-dihydro-8-methoxy-4-oxo-3-quinolinecarboxylic acid

: 151213-40-0,158060-81-2,169533-56-6
(1S,6S)-2,8-diazabicyclo[4.3.0]nonane

: 151096-09-2,1346747-14-5,158060-78-7,195154-07-5,268545-13-7,354812-41-2
moxifloxacin

Guidance literature:: With [BCl₂(4-picoline)][AlCl₄]; triethylamine; In methanol; at 85 ℃; for 6h; Reagent/catalyst; Solvent; Temperature; Catalytic behavior;

Reference yield: 96.0%

: 151213-42-2,158060-81-2,169533-56-6
[R,R]-2,8-diazabicyclo[4.3.0]nonane

: 112811-72-0
1-cyclopropyl-6,7-difluoro-1,4-dihydro-8-methoxy-4-oxo-3-quinolinecarboxylic acid

: 1346747-14-5,158060-78-7,195154-07-5,268545-13-7,354812-41-2
moxifloxacin

Guidance literature:: With nano iron oxide on ZrO₂ coated sulfonic acid; In water; for 0.416667h; Reflux;
DOI:10.2174/1570178615666171226162735

Reference yield: 90.0%

: (4aS-cis)-1-cyclopropyl-7-(2,8 diazabicyclo[4.3.0]non-8-yl)-6-fluoro-8-methoxy-4-oxo-1,4-dihydro-3-quinoline carboxylic aid-O₃,O₄-bis(propyloxy-O)borate.

: 151096-09-2,1346747-14-5,158060-78-7,195154-07-5,268545-13-7,354812-41-2
moxifloxacin

Guidance literature:: (4aS-cis)-1-cyclopropyl-7-(2,8 diazabicyclo[4.3.0]non-8-yl)-6-fluoro-8-methoxy-4-oxo-1,4-dihydro-3-quinoline carboxylic aid-O₃,O₄-bis(propyloxy-O)borate.; With hydrogenchloride; In methanol; water; at 10 - 15 ℃; for 2h; pH=1.0 - 2.0;

With ammonia; In water; at 25 - 75 ℃; for 1.25h; pH=7.5 - 8; Product distribution / selectivity;