6-Bromo-5-chloropyridin-2-amine

Base Information

Chemical Name:6-Bromo-5-chloropyridin-2-amine
CAS No.:1004294-58-9
Molecular Formula:C5H4BrClN2
Molecular Weight:207.457
Hs Code.:2933399090
DSSTox Substance ID:DTXSID80694845
Wikidata:Q72453353
Mol file:1004294-58-9.mol

Synonyms:6-Bromo-5-chloropyridin-2-amine;1004294-58-9;6-BROMO-5-CHLORO-2-PYRIDINAMINE;MFCD16556292;2-Amino-6-bromo-5-chloropyridine;2-Pyridinamine, 6-bromo-5-chloro-;SCHEMBL934504;DTXSID80694845;YRNODZRPIGNGMY-UHFFFAOYSA-N;2-amino-5-chloro-6-bromopyridine;6-Amino-2-bromo-3-chloropyridine;2-Pyridinamine,6-bromo-5-chloro-;AMY40011;AKOS016003364;AKOS032949979;SB74523;AC-25100;DS-16964;SY114543;CS-0005583;FT-0730176;EN300-316531;P16005

Suppliers and Price of 6-Bromo-5-chloropyridin-2-amine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
6-Bromo-5-chloro-2-pyridinamine
100mg
$ 60.00

TRC
6-Bromo-5-chloro-2-pyridinamine
50mg
$ 45.00

SynChem
6-Bromo-5-chloro-pyridin-2-ylamine 95+%
1 g
$ 155.00

SynChem
6-Bromo-5-chloro-pyridin-2-ylamine 95+%
5 g
$ 465.00

SynChem
6-Bromo-5-chloro-pyridin-2-ylamine 95+%
10 g
$ 775.00

Matrix Scientific
6-Bromo-5-chloro-2-pyridinamine 95%
10g
$ 2184.00

Matrix Scientific
6-Bromo-5-chloro-2-pyridinamine 95%
5g
$ 1203.00

Crysdot
6-Bromo-5-chloropyridin-2-amine 98%
1g
$ 119.00

Chemenu
6-Bromo-5-chloro-2-pyridinamine 98%
1g
$ 122.00

Chemcia Scientific
6-Bromo-5-chloro-pyridin-2-ylamine ＞95%
2 G
$ 115.00

Total 55 raw suppliers

Chemical Property of 6-Bromo-5-chloropyridin-2-amine

Chemical Property:

Boiling Point:304.2±37.0 °C(Predicted)
PKA:1.26±0.10(Predicted)
PSA：39.64000
Density:1.834
LogP:2.00980
Storage Temp.:Keep in dark place,Inert atmosphere,Room temperature
XLogP3:2.2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:0
Exact Mass:205.92464
Heavy Atom Count:9
Complexity:101

Purity/Quality:

98%, ^*data from raw suppliers

6-Bromo-5-chloro-2-pyridinamine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=NC(=C1Cl)Br)N

Technology Process of 6-Bromo-5-chloropyridin-2-amine

There total 6 articles about 6-Bromo-5-chloropyridin-2-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 81.0%

: 1004294-57-8
methyl 6-bromo-5-chloropyridin-2-ylcarbamate

: 1004294-58-9
2-amino-6-bromo-5-chloropyridine

Guidance literature:: With methanol; potassium hydroxide; at 20 ℃; for 2h; Heating / reflux;

Reference yield: 75.0%

: 19798-81-3,1184170-10-2
2-Amino-6-bromopyridine

: 1004294-58-9
2-amino-6-bromo-5-chloropyridine

Guidance literature:: With N-chloro-succinimide; In acetonitrile; at 0 - 90 ℃; for 18h;

Reference yield:

: 1004294-55-6
methyl 6-bromo-5-nitropyridin-2-ylcarbamate

: 1004294-58-9
2-amino-6-bromo-5-chloropyridine

Guidance literature:: Multi-step reaction with 3 steps

1: sodium tetrahydroborate / nickel dichloride / methanol / 0.01 h / 0 °C

2: hydrogenchloride; copper(l) chloride; sodium nitrite / water / 2 h / 0 - 20 °C

3: methanol; potassium hydroxide / 2 h / 20 °C / Heating / reflux

With hydrogenchloride; methanol; potassium hydroxide; sodium tetrahydroborate; copper(l) chloride; sodium nitrite; nickel dichloride; In methanol; water;