Ethyl 2-(3-amino-4-fluorophenyl)acetate

Base Information

Chemical Name:Ethyl 2-(3-amino-4-fluorophenyl)acetate
CAS No.:858972-17-5
Molecular Formula:C10H12FNO2
Molecular Weight:197.209
Hs Code.:
Mol file:858972-17-5.mol

Synonyms:ethyl 2-carbethoxyphenoxyacetate;2-Aethoxycarbonylmethoxy-benzoesaeure-aethylester;2-ethoxycarbonylmethoxy-benzoic acid ethyl ester;2-Carbaethoxy-phenoxyessigsaeureaethylester;

Suppliers and Price of Ethyl 2-(3-amino-4-fluorophenyl)acetate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
Ethyl2-(3-amino-4-fluorophenyl)acetate 95+%
1g
$ 546.00

Chemenu
Ethyl2-(3-amino-4-fluorophenyl)acetate 95%
1g
$ 511.00

Total 12 raw suppliers

Chemical Property of Ethyl 2-(3-amino-4-fluorophenyl)acetate

Chemical Property:

Boiling Point:289.5±25.0 °C(Predicted)
PKA:2.97±0.10(Predicted)
PSA：52.32000
Density:1.193±0.06 g/cm3(Predicted)
LogP:2.09470

Purity/Quality:

99% ^*data from raw suppliers

Ethyl2-(3-amino-4-fluorophenyl)acetate 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of Ethyl 2-(3-amino-4-fluorophenyl)acetate

There total 4 articles about Ethyl 2-(3-amino-4-fluorophenyl)acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

: 858972-16-4
ethyl 2-(4-fluoro-3-nitrophenyl)acetate

: 858972-17-5
ethyl 2-(3-amino-4-fluorophenyl)acetate

Guidance literature:: With hydrogen; palladium on activated charcoal; In ethanol; at 20 ℃; atmospheric pressure;
DOI:10.1016/j.tet.2005.04.025

Reference yield:

: 587-88-2
ethyl 2-(4-fluorophenyl)acetate

: 858972-17-5
ethyl 2-(3-amino-4-fluorophenyl)acetate

Guidance literature:: Multi-step reaction with 2 steps

1: 79 percent / H₂SO₄; HNO₃ / 0.58 h / 0 °C

2: 94 percent / hydrogen / Pd/C / ethanol / 20 °C / atmospheric pressure

With sulfuric acid; hydrogen; nitric acid; palladium on activated charcoal; In ethanol;
DOI:10.1016/j.tet.2005.04.025

Reference yield:

: 405-50-5
p-Fluorophenylacetic acid

: 858972-17-5
ethyl 2-(3-amino-4-fluorophenyl)acetate

Guidance literature:: Multi-step reaction with 3 steps

1: 98 percent / H₂SO₄ / 2.5 h / 80 °C

2: 79 percent / H₂SO₄; HNO₃ / 0.58 h / 0 °C

3: 94 percent / hydrogen / Pd/C / ethanol / 20 °C / atmospheric pressure

With sulfuric acid; hydrogen; nitric acid; palladium on activated charcoal; In ethanol;
DOI:10.1016/j.tet.2005.04.025