ACETYL-D,L-DIETHYLALANINE

Base Information

• Chemical Name: ACETYL-D,L-DIETHYLALANINE
• CAS No.: 14328-53-1
• Molecular Formula: C₉H₁₇NO₃
• Molecular Weight: 187.239
• Mol file: 14328-53-1.mol

Synonyms:ACETYL-D,L-DIETHYLALANINE;DL-N-Acetyl-3-ethyl-norvaline

Chemical Property of ACETYL-D,L-DIETHYLALANINE

Chemical Property:

• Vapor Pressure: 8.73E-07mmHg at 25°C
• Melting Point: 185-188°C
• Boiling Point: 378.8°C at 760 mmHg
• Flash Point: 182.9°C
• PSA: 69.89000
• Density: 1.049g/cm³
• LogP: 1.85220
• Storage Temp.: Room Temperature
• Solubility.: Methanol (Slightly), Water (Slightly Heated)

Purity/Quality:

98%Min ^*data from raw suppliers

Acetyl-D,L-diethylalanine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of ACETYL-D,L-DIETHYLALANINE

There total 1 articles about ACETYL-D,L-DIETHYLALANINE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

Hippuric Acid (495-69-2,140480-84-8,21251-67-2,91787-63-2,66407-11-2) + acetic anhydride (108-24-7) + pentan-3-one (96-22-0) → (+/-)-2-Acetylamino-3-aethyl-pentansaeure (14328-53-1)

Guidance literature:

Multistep reaction; (i) NaOAc, Ac₂O, (ii) aq. HI, phosphorus, AcOH, (iii) /BRN= 385737/, AcOH;

Reference yield:

(+/-)-2-Acetylamino-3-aethyl-pentansaeure (14328-53-1) → L-2-Benzyloxycarbonylamino-3-ethyl-pentansaeure-tert.-butyloxycarbonyl-hydrazid

Guidance literature:

Multi-step reaction with 3 steps

1: (enzymatic racemate resolution)

2: aq. NaHCO₃, aq. NaOH

3: DCC / acetonitrile

With sodium hydroxide; sodium hydrogencarbonate; dicyclohexyl-carbodiimide; In acetonitrile;

Reference yield:

(+/-)-2-Acetylamino-3-aethyl-pentansaeure (14328-53-1) → L-2-Benzyloxycarbonylamino-3-ethyl-pentansaeure-(4-nitro-phenylester)

Guidance literature:

Multi-step reaction with 3 steps

1: (enzymatic racemate resolution)

2: aq. NaHCO₃, aq. NaOH

3: DCC / ethyl acetate

With sodium hydroxide; sodium hydrogencarbonate; dicyclohexyl-carbodiimide; In ethyl acetate;

upstream raw materials:

Hippuric Acid

acetic anhydride

pentan-3-one

Downstream raw materials:

2-(S)-amino-3-ethyl-pentanoic acid

3-ethyl-L-norvaline

(S)-2-(benzyloxycarbonylamino)-3-ethylpentanoic acid