2-Amino-8-methoxy-1,2,3,4-tetrahydro-naphthalene-2-carboxylic acid

Base Information

Chemical Name:2-Amino-8-methoxy-1,2,3,4-tetrahydro-naphthalene-2-carboxylic acid
CAS No.:67544-71-2
Molecular Formula:C₁₂H₁₅NO₃
Molecular Weight:221.256
Hs Code.:
DSSTox Substance ID:DTXSID80501383

Synonyms:67544-71-2;2-amino-8-methoxy-1,2,3,4-tetrahydro-naphthalene-2-carboxylic acid;2-Amino-8-methoxy-1,2,3,4-tetrahydronaphthalene-2-carboxylic acid;2-AMINO-8-METHOXY-3,4-DIHYDRO-1H-NAPHTHALENE-2-CARBOXYLIC ACID;2-Amino-8-methoxy-1,2,3,4-tetrahydronaphthalene-2-carboxylicacid;2-IndancarboxylicAcid;DTXSID80501383;MFCD07369844;AKOS022654083;AB32326;AC-9131;AS-36015;CS-0172646;FT-0720114;A13819;2-amino-8-methoxy-1,2,3,4-tetrahydro-naphthalene-2-carboxylic acid, AldrichCPR

Suppliers and Price of 2-Amino-8-methoxy-1,2,3,4-tetrahydro-naphthalene-2-carboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2-Amino-8-methoxy-1,2,3,4-tetrahydro-naphthalene-2-carboxylicAcid
10mg
$ 45.00

Crysdot
2-Amino-8-methoxy-1,2,3,4-tetrahydronaphthalene-2-carboxylicacid 97%
5g
$ 832.00

American Custom Chemicals Corporation
2-AMINO-8-METHOXY-1,2,3,4-TETRAHYDRO-NAPHTHALENE-2-CARBOXYLIC ACID 95.00%
1G
$ 897.44

Alichem
2-Amino-8-methoxy-1,2,3,4-tetrahydronaphthalene-2-carboxylicacid
250mg
$ 161.60

Alichem
2-Amino-8-methoxy-1,2,3,4-tetrahydronaphthalene-2-carboxylicacid
5g
$ 689.52

Alichem
2-Amino-8-methoxy-1,2,3,4-tetrahydronaphthalene-2-carboxylicacid
1g
$ 412.00

AK Scientific
2-Amino-8-methoxy-1,2,3,4-tetrahydro-naphthalene-2-carboxylicacid
250mg
$ 291.00

Total 11 raw suppliers

Chemical Property of 2-Amino-8-methoxy-1,2,3,4-tetrahydro-naphthalene-2-carboxylic acid

Chemical Property:

Vapor Pressure:5.6E-08mmHg at 25°C
Boiling Point:424.9°C at 760 mmHg
Flash Point:210.8°C
PSA：72.55000
Density:1.239g/cm³
LogP:1.66630
XLogP3:-1.2
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:221.10519334
Heavy Atom Count:16
Complexity:281

Purity/Quality:

97% ^*data from raw suppliers

2-Amino-8-methoxy-1,2,3,4-tetrahydro-naphthalene-2-carboxylicAcid ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=CC=CC2=C1CC(CC2)(C(=O)O)N

Technology Process of 2-Amino-8-methoxy-1,2,3,4-tetrahydro-naphthalene-2-carboxylic acid

There total 3 articles about 2-Amino-8-methoxy-1,2,3,4-tetrahydro-naphthalene-2-carboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

: 67544-72-3
3',4'-dihydro-8'-methoxyspiro2,5-dione

: 67544-71-2
2-amino-1,2,3,4-tetrahydro-8-methoxynaphthalene-2-carboxylic acid

Guidance literature:: With barium dihydroxide; In water; at 125 ℃; for 24h;
DOI:10.1002/hlca.19920750522

Reference yield:

: 5309-19-3
8-methoxy-2-tetralone

: 67544-71-2
2-amino-1,2,3,4-tetrahydro-8-methoxynaphthalene-2-carboxylic acid

Guidance literature:: Multi-step reaction with 2 steps

1: 86.6 percent / (NH₄)2CO₃ / ethanol; H₂O / 18 h / 80 °C

2: 85 percent / Ba(OH)2 / H₂O / 24 h / 125 °C

With barium dihydroxide; ammonium carbonate; In ethanol; water;
DOI:10.1002/hlca.19920750522