Tazobactam RC 6

Base Information

Chemical Name:Tazobactam RC 6
CAS No.:85573-73-5
Molecular Formula:C21H20ClNO3S
Molecular Weight:401.914
Hs Code.:
UNII:N3FZV4ADG6
Nikkaji Number:J381.672I
Mol file:85573-73-5.mol

Synonyms:Tazobactam RC 6;85573-73-5;N3FZV4ADG6;4-Thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid, 3-(chloromethyl)-3-methyl-7-oxo-, diphenylmethyl ester, (2S,3R,5R)-;Benzhydryl (2S,3R,5R)-3-(chloromethyl)-3-methyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate;Diphenylmethyl (2S,3R,5R)-3-(chloromethyl)-3-methyl-7-oxo-4-thia-1-azabicyclo(3.2.0)heptane-2-carboxylate;(2S-(2alpha,3beta,5alpha))-3-(Chloromethyl)-3-methyl-7-oxo-4-thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid diphenylmethyl ester;[2S-(2alpha,3beta,5alpha)]-3-(Chloromethyl)-3-methyl-7-oxo-4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic Acid Diphenylmethyl Ester;UNII-N3FZV4ADG6;SCHEMBL3287804;(2S,3R,5R)-Benzhydryl 3-(chloromethyl)-3-methyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate;(2S,3R,5R)-Benzhydryl3-(chloromethyl)-3-methyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate;(2S-(2.ALPHA.,3.BETA.,5.ALPHA.))-3-(CHLOROMETHYL)-3-METHYL-7-OXO-4-THIA-1-AZABICYCLO(3.2.0)HEPTANE-2-CARBOXYLIC ACID DIPHENYLMETHYL ESTER;4-THIA-1-AZABICYCLO(3.2.0)HEPTANE-2-CARBOXYLIC ACID, 3-(CHLOROMETHYL)-3-METHYL-7-OXO-, DIPHENYLMETHYL ESTER, (2S-(2.ALPHA.,3.BETA.,5.ALPHA.))-;4-Thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid, 3-(chloromethyl)-3-methyl-7-oxo-, diphenylmethyl ester, (2S-(2alpha,3beta,5alpha))-

Suppliers and Price of Tazobactam RC 6

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
[2S-(2α,3β,5α)]-3-(Chloromethyl)-3-methyl-7-oxo-4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylicAcidDiphenylmethylEster
500mg
$ 1385.00

Total 10 raw suppliers

Chemical Property of Tazobactam RC 6

Chemical Property:

Boiling Point:565.1±50.0 °C(Predicted)
PKA:-3.84±0.60(Predicted)
PSA：71.91000
Density:1.36±0.1 g/cm3(Predicted)
LogP:3.92840
XLogP3:4
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:6
Exact Mass:401.0852424
Heavy Atom Count:27
Complexity:558

Purity/Quality:

99% ^*data from raw suppliers

[2S-(2α,3β,5α)]-3-(Chloromethyl)-3-methyl-7-oxo-4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylicAcidDiphenylmethylEster ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC1(C(N2C(S1)CC2=O)C(=O)OC(C3=CC=CC=C3)C4=CC=CC=C4)CCl
Isomeric SMILES:C[C@@]1([C@@H](N2[C@H](S1)CC2=O)C(=O)OC(C3=CC=CC=C3)C4=CC=CC=C4)CCl
Uses [2S-(2α,3β,5α)]-3-(Chloromethyl)-3-methyl-7-oxo-4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic Acid Diphenylmethyl Ester is an intermediate used in the synthesis of Tazobactam Sodium Salt-15N3 (T010103), which is a β-Lactamase inhibitor, used with β-lactam antibiotics to enhance their effect.

Technology Process of Tazobactam RC 6

There total 12 articles about Tazobactam RC 6 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%