DIETHYL 1,3-ADAMANTANEDIACETATE

Base Information

• Chemical Name: DIETHYL 1,3-ADAMANTANEDIACETATE
• CAS No.: 81657-07-0
• Molecular Formula: C₁₈H₂₈O₄
• Molecular Weight: 308.418
• Hs Code.: 2917190090
• Mol file: 81657-07-0.mol

Synonyms:Diethyl adamantane-1,3-diacetate

Chemical Property of DIETHYL 1,3-ADAMANTANEDIACETATE

Chemical Property:

• PSA: 52.60000
• Density: 1.112±0.06 g/cm3 (20 oC 760 Torr)
• LogP: 3.47940

Purity/Quality:

98%Min ^*data from raw suppliers

Diethyl2,2'-(adamantane-1,3-diyl)diacetate 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of DIETHYL 1,3-ADAMANTANEDIACETATE

There total 3 articles about DIETHYL 1,3-ADAMANTANEDIACETATE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

ethanol (64-17-5) + 1,3-adamantane diacetic acid (17768-28-4) → (3-ethoxycarbonylmethyl-adamantan-1-yl)-acetic acid ethyl ester (81657-07-0)

Guidance literature:

With sulfuric acid; for 5h; Inert atmosphere; Reflux;

DOI:10.1021/om500014z

Reference yield:

1,3-adamantane diacetic acid (17768-28-4) → (3-ethoxycarbonylmethyl-adamantan-1-yl)-acetic acid ethyl ester (81657-07-0)

Guidance literature:

With thionyl chloride;

Reference yield:

ethanol (64-17-5) + 1,3-adamantanediacetyl dichloride (31898-14-3) → (3-ethoxycarbonylmethyl-adamantan-1-yl)-acetic acid ethyl ester (81657-07-0)

Guidance literature:

at 0 ℃; Reflux;

DOI:10.1016/j.bmcl.2010.07.078

upstream raw materials:

ethanol

1,3-adamantane diacetic acid

1,3-adamantanediacetyl dichloride

Downstream raw materials:

2-[3-(2-hydroxy-ethyl)-adamantan-1-yl]-ethanol

Refernces

• 1、 Grin?, I. S.,Ivleva, E. A.,Klimochkin, Yu. N.,Uchaev, I. S.. "Oxidation of Deactivated Cage Substrates in the System H2SO4–HNO3". . p. 412 - 421. Retrieved 2020/04/27.
• 2、 Majerski, Zdenko,Skare, Danko,Vulic, Ljubica. "A CONVENIENT SYNTHESIS OF 1,3-DIVINYLADAMANTANE". . p. 51 - 56. Retrieved 2007/10/02.