2,5-ANHYDRO-1,3-O-ISOPROPYLIDENE-6-O-TRITYL-D-GLUCITOL

Base Information

• Chemical Name: 2,5-ANHYDRO-1,3-O-ISOPROPYLIDENE-6-O-TRITYL-D-GLUCITOL
• CAS No.: 65758-50-1
• Molecular Formula: C27H28O5
• Molecular Weight: 432.513
• Mol file: 65758-50-1.mol

Synonyms:2,5-Anhydro-1,3-O-(1-Methylethylidene)-6-O-(triphenylMethyl)-D-glucitol

Chemical Property of 2,5-ANHYDRO-1,3-O-ISOPROPYLIDENE-6-O-TRITYL-D-GLUCITOL

Chemical Property:

• Vapor Pressure: 0mmHg at 25°C
• Melting Point: 185-186°C
• Boiling Point: 576.083°C at 760 mmHg
• Flash Point: 302.204°C
• PSA: 57.15000
• Density: 1.172g/cm³
• LogP: 4.23240
• Storage Temp.: -20°C Freezer

Purity/Quality:

98%Min ^*data from raw suppliers

2,5-Anhydro-1,3-O-isopropylidene-6-O-trityl-D-glucitol ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2,5-ANHYDRO-1,3-O-ISOPROPYLIDENE-6-O-TRITYL-D-GLUCITOL

There total 2 articles about 2,5-ANHYDRO-1,3-O-ISOPROPYLIDENE-6-O-TRITYL-D-GLUCITOL which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2,5-anhydro-1,3-O-isopropylidene-D-glucitol (65729-81-9) + trityl chloride (76-83-5) → 2,5-anhydro-1,3-O-isoprpylidene-6-O-triphenylmethyl-D-glucitol (65758-50-1)

Guidance literature:

With pyridine;

DOI:10.1080/15257770903306518

Reference yield:

→ 2,5-anhydro-1,3-O-isoprpylidene-6-O-triphenylmethyl-D-glucitol (65758-50-1)

Guidance literature:

Diol 3a, Tritylchlorid;

DOI:10.1016/S0008-6215(00)83181-X

Reference yield:

2,5-anhydro-1,3-O-isoprpylidene-6-O-triphenylmethyl-D-glucitol (65758-50-1) → 2,5-Anhydro-1-O-trityl-D-mannit (68774-48-1)

Guidance literature:

Multi-step reaction with 2 steps

1: 98 percent / 30 percent HBr / acetic acid / 0 °C

2: pyridine

With pyridine; hydrogen bromide; In acetic acid;

DOI:10.1016/0008-6215(84)85399-9

upstream raw materials:

2,5-anhydro-1,3-O-isopropylidene-D-glucitol

trityl chloride

Downstream raw materials:

2,5-Anhydro-1-O-trityl-D-mannit

2,5-anhydro-1,6-bis-O-(triphenylmethyl)-D-glucitol

Refernces