4,6-DICHLORO-2-(METHYLTHIO)PYRIMIDINE-5-CARBOXAMIDE

Base Information

Chemical Name:4,6-DICHLORO-2-(METHYLTHIO)PYRIMIDINE-5-CARBOXAMIDE
CAS No.:313339-36-5
Molecular Formula:C6H5Cl2N3OS
Molecular Weight:238.0944
Hs Code.:2933599090
Mol file:313339-36-5.mol

Synonyms:4,6-Dichloro-2-(methylsulfanyl)pyrimidine-5-carboxamide; 5-Pyrimidinecarboxamide, 4,6-dichloro-2-(methylthio)-

Suppliers and Price of 4,6-DICHLORO-2-(METHYLTHIO)PYRIMIDINE-5-CARBOXAMIDE

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Sigma-Aldrich
4,6-Dichloro-2-(methylthio)pyrimidine-5-carboxamide 97%
1g
$ 81.20

Crysdot
4,6-Dichloro-2-(methylthio)pyrimidine-5-carboxamide 95+%
5g
$ 506.00

Chemenu
4,6-Dichloro-2-(methylthio)pyrimidine-5-carboxamide 95%
5g
$ 473.00

American Custom Chemicals Corporation
4,6-DICHLORO-2-(METHYLTHIO)PYRIMIDINE-5-CARBOXAMIDE 95.00%
5G
$ 3811.50

Total 12 raw suppliers

Chemical Property of 4,6-DICHLORO-2-(METHYLTHIO)PYRIMIDINE-5-CARBOXAMIDE

Chemical Property:

Vapor Pressure:0mmHg at 25°C
Melting Point:239-244°C
Boiling Point:351.378°C at 760 mmHg
Flash Point:166.308°C
PSA：95.16000
Density:1.636g/cm³
LogP:2.48840

Purity/Quality:

97% ^*data from raw suppliers

4,6-Dichloro-2-(methylthio)pyrimidine-5-carboxamide 97% ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi
Hazard Codes:Xi
Statements: 43
Safety Statements: 36/37

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 4,6-DICHLORO-2-(METHYLTHIO)PYRIMIDINE-5-CARBOXAMIDE

There total 3 articles about 4,6-DICHLORO-2-(METHYLTHIO)PYRIMIDINE-5-CARBOXAMIDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 313339-35-4
4,6-dichloro-2-(methylsulfanyl)pyrimidine-5-carboxylic acid

: 313339-36-5
4,6-dichloro-2-(methylsulfanyl)pyrimidine-5-carboxamide

Guidance literature:: 4,6-dichloro-2-(methylsulfanyl)pyrimidine-5-carboxylic acid; With thionyl chloride; for 1h; Reflux;

With ammonia; In tetrahydrofuran; water; at 0 - 20 ℃; for 2h;

Reference yield:

: 1979-98-2
4,6-dihydroxy-2-methylmercaptopyrimidine

: 313339-36-5
4,6-dichloro-2-(methylsulfanyl)pyrimidine-5-carboxamide

Guidance literature:: Multi-step reaction with 3 steps

1.1: trichlorophosphate / 4 h / 120 °C

2.1: diisopropylamine; n-butyllithium / hexane; tetrahydrofuran / 3 h / -78 °C

2.2: 0.5 h / 20 °C

2.3: 20 °C / pH 1

3.1: thionyl chloride / 1 h / Reflux

3.2: 2 h / 0 - 20 °C

With n-butyllithium; thionyl chloride; diisopropylamine; trichlorophosphate; In tetrahydrofuran; hexane;

Reference yield:

: 6299-25-8
4,6-Dichloro-2-(methylthio)pyrimidine

: 313339-36-5
4,6-dichloro-2-(methylsulfanyl)pyrimidine-5-carboxamide

Guidance literature:: Multi-step reaction with 2 steps

1.1: diisopropylamine; n-butyllithium / hexane; tetrahydrofuran / 3 h / -78 °C

1.2: 0.5 h / 20 °C

1.3: 20 °C / pH 1

2.1: thionyl chloride / 1 h / Reflux

2.2: 2 h / 0 - 20 °C

With n-butyllithium; thionyl chloride; diisopropylamine; In tetrahydrofuran; hexane;