Di-tert-Butyl 2,6-diazaspiro[3.3]heptane-2,6-dicarboxylate

Base Information

• Chemical Name: Di-tert-Butyl 2,6-diazaspiro[3.3]heptane-2,6-dicarboxylate
• CAS No.: 1150618-17-9
• Molecular Formula: C15H26N2O4
• Molecular Weight: 298.38
• Hs Code.: 2933990090
• Mol file: 1150618-17-9.mol

Synonyms:2,6-diazaspiro[3.3]heptane-2,6-dicarboxylic acid, bis(1,1-dimethylethyl) ester;

Chemical Property of Di-tert-Butyl 2,6-diazaspiro[3.3]heptane-2,6-dicarboxylate

Chemical Property:

• Boiling Point: 379 °C at 760 mmHg
• Flash Point: 183 °C
• PSA: 59.08000
• Density: 1.15 g/cm³
• LogP: 2.35000
• Storage Temp.: 2-8°C

Purity/Quality:

97% ^*data from raw suppliers

Di-tert-butyl2,6-diazaspiro[3.3]heptane-2,6-dicarboxylate 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Di-tert-Butyl 2,6-diazaspiro[3.3]heptane-2,6-dicarboxylate

There total 1 articles about Di-tert-Butyl 2,6-diazaspiro[3.3]heptane-2,6-dicarboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

di-tert-butyl dicarbonate (24424-99-5) + 2,2-bis-bromomethyl-propanediyldiamine; dihydrobromide (135380-46-0) → di-tert-butyl 2,6-diazaspiro[3.3]heptane-2,6-dicarboxylate (1150618-17-9)

Guidance literature:

2,2-bis-bromomethyl-propanediyldiamine; dihydrobromide; With sodium hydroxide; In water; at 95 - 100 ℃;

di-tert-butyl dicarbonate; With sodium carbonate; In tetrahydrofuran; water; at 20 ℃; for 16h;

Reference yield:

di-tert-butyl 2,6-diazaspiro[3.3]heptane-2,6-dicarboxylate (1150618-17-9) + oxalic acid (144-62-7,97993-78-7) → 2,6-diazaspiro[3.3]heptane-2-carboxylic acid tert-butyl ester oxalate (1227382-01-5,1041026-71-4)

Guidance literature:

di-tert-butyl 2,6-diazaspiro[3.3]heptane-2,6-dicarboxylate; With methanol; acetyl chloride; at 20 ℃; for 20h; Inert atmosphere;

With potassium hydroxide; In methanol; at 30 ℃;

oxalic acid; In diethyl ether; at 20 ℃; for 1h;

upstream raw materials:

di-tert-butyl dicarbonate

2,2-bis-bromomethyl-propanediyldiamine; dihydrobromide

Downstream raw materials:

2,6-diazaspiro[3.3]heptane-2-carboxylic acid tert-butyl ester oxalate