(3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl 4-nitrophenyl carbonate

Base Information

Chemical Name:(3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl 4-nitrophenyl carbonate
CAS No.:192725-55-6
Molecular Formula:C13H13NO7
Molecular Weight:295.249
Hs Code.:
Mol file:192725-55-6.mol

Synonyms:Carbonic acid (3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl 4-nitrophenyl ester;

Suppliers and Price of (3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl 4-nitrophenyl carbonate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 11 raw suppliers

Chemical Property of (3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl 4-nitrophenyl carbonate

Chemical Property:

Purity/Quality:: 99%, ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of (3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl 4-nitrophenyl carbonate

There total 20 articles about (3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl 4-nitrophenyl carbonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

: 7693-46-1
4-Nitrophenyl chloroformate

: 156928-09-5
(3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-ol

: 192725-55-6,252873-01-1,252873-35-1
(3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl-(4-nitrophenyl)carbonic acid

Guidance literature:: With pyridine; In dichloromethane; at 0 - 23 ℃; for 12h; Inert atmosphere;
DOI:10.1021/acs.joc.0c02396

Reference yield: 55.0%

: 5070-13-3
bis-(p-nitrophenyl) carbonate

: 156928-09-5
(3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-ol

: 192725-55-6,252873-01-1,252873-35-1
(3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl-(4-nitrophenyl)carbonic acid

Guidance literature:: With triethylamine; In dichloromethane; at 20 - 25 ℃;

Reference yield:

: 5070-13-3
bis-(p-nitrophenyl) carbonate

: (3SR,3aRS,6aSR)-3-hydroxy-4H-hexahydrofuro<2,3-b>furan

: 192725-55-6,252873-01-1,252873-35-1
(3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl-(4-nitrophenyl)carbonic acid

Guidance literature:: (3SR,3aRS,6aSR)-3-hydroxy-4H-hexahydrofuro<2,3-b>furan; With acetic anhydride; In 1,2-dimethoxyethane; Inert atmosphere; Resolution of racemate; Large scale;

bis-(p-nitrophenyl) carbonate; With triethylamine; In dichloromethane; at 20 - 25 ℃; for 48h; Time; stereoselective reaction; Inert atmosphere; Large scale;
DOI:10.1021/op700160a