3-Acetyl-1,2-O-isopropylidene-6-O-trityl-α-D-galactofuranose

Base Information

• Chemical Name: 3-Acetyl-1,2-O-isopropylidene-6-O-trityl-α-D-galactofuranose
• CAS No.: 109680-97-9
• Molecular Formula: C30H32O7
• Molecular Weight: 504.5709
• Mol file: 109680-97-9.mol

Synonyms:3-Acetyl-1,2-O-isopropylidene-6-O-trityl-α-D-galactofuranose;1,2-O-(1-Methylethylidene)-6-O-(triphenylMethyl)-α-D-galactofuranose 3-Acetate

Chemical Property of 3-Acetyl-1,2-O-isopropylidene-6-O-trityl-α-D-galactofuranose

Chemical Property:

• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.615
• Boiling Point: 601.966°C at 760 mmHg
• Flash Point: 192.8°C
• PSA: 83.45000
• Density: 1.277g/cm³
• LogP: 4.16410
• Solubility.: Chloroform, Ethyl Acetate, Methanol

Purity/Quality:

99% ^*data from raw suppliers

3-Acetyl-1,2-O-isopropylidene-6-O-trityl-α-D-galactofuranose ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3-Acetyl-1,2-O-isopropylidene-6-O-trityl-α-D-galactofuranose

There total 4 articles about 3-Acetyl-1,2-O-isopropylidene-6-O-trityl-α-D-galactofuranose which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

trityl chloride (76-83-5) + 3-O-acetyl-1,2-O-isopropylidene-α-D-galactofuranose (109680-96-8) → 3-O-acetyl-1,2-O-isopropylidene-6-O-trityl-α-D-galactofuranose (109680-97-9)

Guidance literature:

With pyridine; at 70 ℃; for 7h;

DOI:10.1016/S0008-6215(00)90138-1

Reference yield:

1,2:5,6-di-O-isoproylidene-3-O-tosyl-α-D-gulofuranose (19131-06-7) → 3-O-acetyl-1,2-O-isopropylidene-6-O-trityl-α-D-galactofuranose (109680-97-9)

Guidance literature:

Multi-step reaction with 3 steps

1: 78 percent / chlorobenzene / 5 h / Heating

2: 50percent aq. AcOH / 5 h / Ambient temperature; concentrated at 25 deg C

3: 98 percent / pyridine / 7 h / 70 °C

With pyridine; acetic acid; In chlorobenzene;

DOI:10.1016/S0008-6215(00)90138-1

Reference yield:

3-O-acetyl-1,2:5,6-di-O-isopropylidene-α-D-galactofuranose (38166-65-3) → 3-O-acetyl-1,2-O-isopropylidene-6-O-trityl-α-D-galactofuranose (109680-97-9)

Guidance literature:

Multi-step reaction with 2 steps

1: 50percent aq. AcOH / 5 h / Ambient temperature; concentrated at 25 deg C

2: 98 percent / pyridine / 7 h / 70 °C

With pyridine; acetic acid;

DOI:10.1016/S0008-6215(00)90138-1

upstream raw materials:

3-O-acetyl-1,2-O-isopropylidene-α-D-glucofuranose

trityl chloride

3-O-acetyl-1,2-O-isopropylidene-α-D-galactofuranose

3-O-acetyl-1,2:5,6-di-O-isopropylidene-α-D-galactofuranose

Downstream raw materials:

3-O-acetyl-1,2-O-isopropylidene-6-O-trityl-β-L-arabino-hexofuranos-5-ulose

5-amino-5-deoxy-1,2-O-isoproylidene-6-O-trityl-α-D-galactofuranose

5-amino-5-deoxy-1,2-O-isoproylidene-6-O-trityl-β-L-altrofuranose

Acetic acid (3aR,5S,6S,6aR)-5-{1-[(Z)-hydroxyimino]-2-trityloxy-ethyl}-2,2-dimethyl-tetrahydro-furo[2,3-d][1,3]dioxol-6-yl ester