4-Bromo-2-methoxyphenylboronic acid

Base Information

Chemical Name:4-Bromo-2-methoxyphenylboronic acid
CAS No.:889849-21-2
Molecular Formula:C7H8BBrO3
Molecular Weight:230.854
Hs Code.:2931900090
DSSTox Substance ID:DTXSID50681883
Wikidata:Q82606062
Mol file:889849-21-2.mol

Synonyms:4-BROMO-2-METHOXYPHENYLBORONIC ACID;889849-21-2;(4-Bromo-2-methoxyphenyl)boronic acid;MFCD11856025;4-bromo-2-methoxyphenylboronicacid;(4-Bromo-2-methoxy-phenyl)boronic acid;SCHEMBL4908473;DTXSID50681883;VJWDDRPEDLXFLY-UHFFFAOYSA-N;AMY36736;4-Bromo-2-methoxyphenyl)boronicacid;(4-Bromo-2-methoxyphenyl)boronicacid;4-bromo2-methoxy-phenyl boronic acid;AKOS015835526;SY060752;CS-0130106;FT-0726013;F15502;A861360;J-514668

Suppliers and Price of 4-Bromo-2-methoxyphenylboronic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
4-Bromo-2-methoxyphenylboronicacid
500mg
$ 125.00

Matrix Scientific
(4-Bromo-2-methoxyphenyl)boronic acid 95+%
1g
$ 420.00

Matrix Scientific
(4-Bromo-2-methoxyphenyl)boronic acid 95+%
250mg
$ 189.00

Crysdot
(4-Bromo-2-methoxyphenyl)boronicacid 97%
1g
$ 140.00

Crysdot
(4-Bromo-2-methoxyphenyl)boronicacid 97%
5g
$ 480.00

Biosynth Carbosynth
4-Bromo-2-methoxyphenylboronic acid
2 g
$ 320.00

Biosynth Carbosynth
4-Bromo-2-methoxyphenylboronic acid
100 mg
$ 42.00

Biosynth Carbosynth
4-Bromo-2-methoxyphenylboronic acid
1 g
$ 180.00

Biosynth Carbosynth
4-Bromo-2-methoxyphenylboronic acid
250 mg
$ 75.00

Biosynth Carbosynth
4-Bromo-2-methoxyphenylboronic acid
500 mg
$ 115.00

Total 30 raw suppliers

Chemical Property of 4-Bromo-2-methoxyphenylboronic acid

Chemical Property:

Boiling Point:354.5±52.0 °C at 760 mmHg
PKA:8.34±0.58(Predicted)
Flash Point:168.2±30.7 °C
PSA：49.69000
Density:1.6±0.1 g/cm³
LogP:0.13750
Storage Temp.:Room temperature.
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:229.97499
Heavy Atom Count:12
Complexity:145

Purity/Quality:

97% ^*data from raw suppliers

4-Bromo-2-methoxyphenylboronicacid ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:B(C1=C(C=C(C=C1)Br)OC)(O)O

Technology Process of 4-Bromo-2-methoxyphenylboronic acid

There total 4 articles about 4-Bromo-2-methoxyphenylboronic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 68.0%

: 791642-68-7
4-bromo-1-iodo-2-methoxybenzene

: 889849-21-2
(4-bromo-2-methoxyphenyl)boronic acid

Guidance literature:: 4-bromo-1-iodo-2-methoxybenzene; With n-butyllithium; In tetrahydrofuran; hexanes; at -80 ℃; Inert atmosphere;

With Trimethyl borate; In tetrahydrofuran; hexanes; at -80 - 20 ℃; Inert atmosphere;

With hydrogenchloride; In tetrahydrofuran; hexanes; water; at 20 ℃; Inert atmosphere;
DOI:10.1021/jo102228j

Reference yield:

: 791642-68-7
4-bromo-1-iodo-2-methoxybenzene

: 25015-63-8
4,4,5,5-tetramethyl-[1,3,2]-dioxaboralane

: 889849-21-2
(4-bromo-2-methoxyphenyl)boronic acid

: C₁₃H₁₈BBrO₃

Guidance literature:: With dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH₂Cl₂; triethylamine; In 1,4-dioxane; at 80 ℃; for 16h; Overall yield = 72 %;
DOI:10.1021/acs.joc.7b03009

Reference yield:

: 59557-91-4
4-bromo-2-methoxyaniline

: 889849-21-2
(4-bromo-2-methoxyphenyl)boronic acid

Guidance literature:: Multi-step reaction with 2 steps

1.1: sulfuric acid; potassium iodide; sodium nitrite / Inert atmosphere

2.1: n-butyllithium / tetrahydrofuran; hexanes / -80 °C / Inert atmosphere

2.2: -80 - 20 °C / Inert atmosphere

2.3: 20 °C / Inert atmosphere

With n-butyllithium; sulfuric acid; potassium iodide; sodium nitrite; In tetrahydrofuran; hexanes; 1.1: Sandmeyer reaction;
DOI:10.1021/jo102228j