3-(5-Fluoropyridin-2-yl)acrylic acid hydrochloride

Base Information

• Chemical Name: 3-(5-Fluoropyridin-2-yl)acrylic acid hydrochloride
• CAS No.: 917760-91-9
• Molecular Formula: C₈H₆FNO₂*ClH
• Molecular Weight: 203.6
• Hs Code.: 2933399990
• Mol file: 917760-91-9.mol

Synonyms:3-(5-fluoropyridin-2-yl)prop-2-enoic acid,hydrochloride;

Chemical Property of 3-(5-Fluoropyridin-2-yl)acrylic acid hydrochloride

Chemical Property:

• PSA: 50.19000
• LogP: 2.12050
• Storage Temp.: Sealed in dry,Room Temperature

Purity/Quality:

97% ^*data from raw suppliers

3-(5-Fluoropyridin-2-yl)acrylicacidhydrochloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3-(5-Fluoropyridin-2-yl)acrylic acid hydrochloride

There total 1 articles about 3-(5-Fluoropyridin-2-yl)acrylic acid hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

5-fluoropicolinaldehyde (31181-88-1) + malonic acid (141-82-2) → (E)-3-(5-fluoropyridin-2-yl)acrylic acid hydrochloride (917760-91-9)

Guidance literature:

5-fluoropicolinaldehyde; malonic acid; With piperidine; pyridine; at 20 - 100 ℃; for 20h;

With hydrogenchloride; water; at 0 ℃;

upstream raw materials:

5-fluoropicolinaldehyde

malonic acid