7-Methyl-1H-pyrrolo[3,2-b]pyridin-2(3H)-one

Base Information

Chemical Name:7-Methyl-1H-pyrrolo[3,2-b]pyridin-2(3H)-one
CAS No.:56057-25-1
Molecular Formula:C8H8N2O
Molecular Weight:148.164
Hs Code.:2933990090
DSSTox Substance ID:DTXSID40480847
Wikidata:Q72465654
Mol file:56057-25-1.mol

Synonyms:7-Methyl-1H-pyrrolo[3,2-b]pyridin-2(3H)-one;56057-25-1;7-methyl-4-aza-2-oxindole;7-methyl-1,3-dihydropyrrolo[3,2-b]pyridin-2-one;SCHEMBL659718;AMY2860;DTXSID40480847;RPQWKYDZGOEUFR-UHFFFAOYSA-N;MFCD12924242;AKOS015998746;DS-16322;CS-0054268;FT-0687306;C75634;7-methyl-1,3-dihydro-2H-pyrrolo[3,2-b]pyridin-2-one;7-Methyl-1H-pyrrolo[3 pound not2-b]pyridin-2(3H)-one

Suppliers and Price of 7-Methyl-1H-pyrrolo[3,2-b]pyridin-2(3H)-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
7-methyl-1H-pyrrolo[3,2-b]pyridin-2(3H)-one
100mg
$ 240.00

TRC
7-methyl-1H-pyrrolo[3,2-b]pyridin-2(3H)-one
10mg
$ 45.00

Crysdot
7-Methyl-1H-pyrrolo[3,2-b]pyridin-2(3H)-one 95+%
1g
$ 632.00

Chemenu
7-methyl-1,3-dihydro-2H-pyrrolo[3,2-b]pyridin-2-one 95%
1g
$ 597.00

Ambeed
7-Methyl-1H-pyrrolo[3,2-b]pyridin-2(3H)-one 95+%
250mg
$ 243.00

Ambeed
7-Methyl-1H-pyrrolo[3,2-b]pyridin-2(3H)-one 95+%
100mg
$ 152.00

Ambeed
7-Methyl-1H-pyrrolo[3,2-b]pyridin-2(3H)-one 95+%
1g
$ 608.00

Alichem
7-Methyl-1H-pyrrolo[3,2-b]pyridin-2(3H)-one
1g
$ 669.90

Alichem
7-Methyl-1H-pyrrolo[3,2-b]pyridin-2(3H)-one
100mg
$ 176.00

Alichem
7-Methyl-1H-pyrrolo[3,2-b]pyridin-2(3H)-one
250mg
$ 262.65

Total 25 raw suppliers

Chemical Property of 7-Methyl-1H-pyrrolo[3,2-b]pyridin-2(3H)-one

Chemical Property:

Melting Point:264℃
Boiling Point:334.0±42.0 °C(Predicted)
PKA:13.05±0.20(Predicted)
PSA：41.99000
Density:1.228
LogP:1.02260
Storage Temp.:Sealed in dry,Room Temperature
XLogP3:0.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:0
Exact Mass:148.063662883
Heavy Atom Count:11
Complexity:181

Purity/Quality:

99%, ^*data from raw suppliers

7-methyl-1H-pyrrolo[3,2-b]pyridin-2(3H)-one ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=C2C(=NC=C1)CC(=O)N2

Technology Process of 7-Methyl-1H-pyrrolo[3,2-b]pyridin-2(3H)-one

There total 1 articles about 7-Methyl-1H-pyrrolo[3,2-b]pyridin-2(3H)-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 56057-25-1
7-methyl-1,3-dihydro-pyrrolo[3,2-b]pyridin-2-one

Guidance literature:: Verb. IIIb, HCl, Cyclisierung;

Reference yield: 58.0%

: 85070-48-0
2-fluoro-3-chlorobenzaldehyde

: 56057-25-1
7-methyl-1,3-dihydro-pyrrolo[3,2-b]pyridin-2-one

: 1360822-00-9
E/Z-3-(3-chloro-2-fluorobenzylidene)-7-methyl-1,3-dihydropyrrolo[3,2-b]pyridin-2-one

Guidance literature:: With piperidine; In methanol; at 50 ℃;

Reference yield:

: 56057-25-1
7-methyl-1,3-dihydro-pyrrolo[3,2-b]pyridin-2-one

: rac-4-((2S,3S,4S,5R)-4-(3-chloro-2-fluorophenyl)-7'-methyl-2-neopentyl-2'-oxo-1',2'-dihydrospiro[pyrrolidine-3,3'-pyrrolo[3,2-b]pyridine]-5-ylcarboxamido)-3-methoxybenzoic acid

Guidance literature:: Multi-step reaction with 3 steps

1.1: piperidine / methanol / 50 °C

2.1: lithium hydroxide / tetrahydrofuran / 0.17 h / 40 °C

2.2: 20 h / 40 °C

3.1: lithium hydroxide monohydrate / tetrahydrofuran / 20 °C

With piperidine; lithium hydroxide monohydrate; lithium hydroxide; In tetrahydrofuran; methanol;