1-Boc-3-Cbz-aminopyrrolidine

Base Information

Chemical Name:1-Boc-3-Cbz-aminopyrrolidine
CAS No.:325775-36-8
Molecular Formula:C17H24N2O4
Molecular Weight:320.389
Hs Code.:2933990090
Mol file:325775-36-8.mol

Synonyms:tert-Butyl 3-{[(benzyloxy)carbonyl]amino}pyrrolidine-1-carboxylate;3-Benzyloxycarbonylamino-pyrrolidine-1-carboxylic acid tert-butyl ester;

Suppliers and Price of 1-Boc-3-Cbz-aminopyrrolidine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
1-Boc-3-Cbz-aminopyrrolidine 97%
1g
$ 377.00

Chemenu
tert-butyl3-(((benzyloxy)carbonyl)amino)pyrrolidine-1-carboxylate 97%
1g
$ 356.00

American Custom Chemicals Corporation
1-BOC-3-CBZ-AMINOPYRROLIDINE 95.00%
1G
$ 903.50

Alichem
1-Boc-3-Cbz-aminopyrrolidine
1g
$ 765.00

AK Scientific
1-Boc-3-Cbz-aminopyrrolidine
250mg
$ 300.00

Total 14 raw suppliers

Chemical Property of 1-Boc-3-Cbz-aminopyrrolidine

Chemical Property:

Boiling Point:458.135 °C at 760 mmHg
Flash Point:230.872 °C
PSA：67.87000
Density:1.174 g/cm³
LogP:3.25100
Storage Temp.:2-8°C

Purity/Quality:

97% ^*data from raw suppliers

1-Boc-3-Cbz-aminopyrrolidine 97% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 1-Boc-3-Cbz-aminopyrrolidine

There total 6 articles about 1-Boc-3-Cbz-aminopyrrolidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.2%

: 501-53-1,94274-21-2
benzyl chloroformate

: 186550-13-0
3-amino-1-(t-butoxycarbonyl)pyrrolidine

: 325775-36-8,247569-07-9
tert-butyl 3-{[(benzyloxy)carbonyl]amino}-1-pyrrolidinecarboxylate

Guidance literature:: With N-ethyl-N,N-diisopropylamine; In dichloromethane; for 3h; Cooling with ice;
DOI:10.1039/c8ob00286j

Reference yield:

: 72925-16-7,72983-31-4,140148-70-5,59378-75-5
1-boc-pyrrolidine-3-carboxylic acid

: 100-51-6,185532-71-2
benzyl alcohol

: 325775-36-8,247569-07-9
tert-butyl 3-{[(benzyloxy)carbonyl]amino}-1-pyrrolidinecarboxylate

Guidance literature:: 1-boc-pyrrolidine-3-carboxylic acid; With diphenyl phosphoryl azide; triethylamine; In toluene; at 20 ℃; for 1.16667h; Heating / reflux;

benzyl alcohol; In toluene; for 14h; Heating / reflux;